RAD21 and RPL10

Data Source:
BioGRID (two hybrid)

		RAD21	RPL10
Description		RAD21 cohesin complex component	ribosomal protein L10
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Synaptonemal Complex Spindle Pole Nucleoplasm Chromosome Cytosol Cohesin Complex Membrane Nuclear Matrix Nuclear Mitotic Cohesin Complex Nuclear Meiotic Cohesin Complex	Nucleus Endoplasmic Reticulum Smooth Endoplasmic Reticulum Cytosol Membrane Cytosolic Large Ribosomal Subunit Protein-containing Complex
	Molecular Function	Chromatin Binding Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Translation Regulator Activity
	Biological Process	Double-strand Break Repair DNA Recombination Regulation Of Transcription By RNA Polymerase II Apoptotic Process Mitotic Sister Chromatid Cohesion Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Multicellular Organism Development Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Sister Chromatid Cohesion Cell Division Protein Localization To Chromatin Replication-born Double-strand Break Repair Via Sister Chromatid Exchange	Ribosomal Large Subunit Assembly Negative Regulation Of Transcription By RNA Polymerase II Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Negative Regulation Of Apoptotic Process Embryonic Brain Development
Pathways		Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			Artenimol
Diseases
GWAS		Menopause (age at onset) ( 29773799)
Interacting Genes		30 interacting genes: CAPN1 CASP7 CFL1 CSTB DISC1 DYNLT1 FHL3 FLNB HNRNPH2 IL7R MSRB2 MT-CO2 NUMA1 PPP1R15A PPP1R15B PTEN RPL10 RPL13 RPL35A SMARCA5 SMC1A SSU72 STAG1 STAG2 SUMO2 TMSB4X TNFRSF14 WAPL WNT2B ZNF80	14 interacting genes: DUX4 ERCC6 FYN HCK LYN MAPK6 PRKCA PTEN RAD21 SRC SUMO2 TAB1 TBPL1 YES1
Entrez ID		5885	6134
HPRD ID		05924	02421
Ensembl ID		ENSG00000164754	ENSG00000147403
Uniprot IDs		A0A024R9J0 O60216	A0A087WV22 P27635 X5D2T3
PDB IDs		4PJU 4PJW 4PK7 6QNX 6RRC 6RRK 6WG3 6WGE	2PA2 5AJ0 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6W6L
Enriched GO Terms of Interacting Partners?
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