RAB27B and SYTL2

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		RAB27B	SYTL2
Description		RAB27B, member RAS oncogene family	synaptotagmin like 2
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GO Annotations	Cellular Component	Late Endosome Golgi Stack Plasma Membrane Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane Axon Cytoplasm	Cytoplasm Plasma Membrane Membrane Extrinsic Component Of Plasma Membrane Melanosome Exocytic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatase Binding Neurexin Family Protein Binding
	Biological Process	Platelet Degranulation Melanosome Transport Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport	Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Negative Regulation Of Phosphatase Activity Vesicle-mediated Transport
Pathways		Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Adult body size ( 32376654) Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Pallidum volume ( 31530798) Refractive error ( 32231278)
Interacting Genes		11 interacting genes: DHPS GORASP2 MLPH MYRIP RPH3A RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D	9 interacting genes: FBXO25 LNX1 MORN4 MTERF1 NRXN1 PPP1CA RAB27A RAB27B YIF1A
Entrez ID		5874	54843
HPRD ID		04846	10260
Ensembl ID		ENSG00000041353	ENSG00000137501
Uniprot IDs		O00194	A0A0U1RR07 Q9HCH5
PDB IDs		2F7S	3BC1
Enriched GO Terms of Interacting Partners?
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