RAB4A and RBSN

Data Source:
HPRD (in vivo, in vitro)

		RAB4A	RBSN
Description		RAB4A, member RAS oncogene family	rabenosyn, RAB effector
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GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane Vesicle Insulin-responsive Compartment Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Postsynaptic Recycling Endosome Anchored Component Of Synaptic Vesicle Membrane	Endosome Cytosol Plasma Membrane Endosome Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	ATPase Activator Activity GTPase Activity Protein Binding GTP Binding GDP Binding Syntaxin Binding Ionotropic Glutamate Receptor Binding ATPase Binding	Protein Binding Zinc Ion Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Positive Regulation Of ATPase Activity	Blood Coagulation Protein Transport Endosomal Transport Early Endosome To Golgi Transport Golgi To Lysosome Transport Regulation Of Golgi Organization
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane TBC/RABGAPs RAB geranylgeranylation MET receptor recycling	Toll Like Receptor 9 (TLR9) Cascade Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Aging ( 22773346) Leukoderma in response to rhododendrol ( 32558222) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Mercury levels ( 26025379) Response to antidepressants in depression ( 27622933)
Interacting Genes		33 interacting genes: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 FAM71C GDI2 GRIPAP1 HACE1 IDH3A KCTD7 KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830	14 interacting genes: AGTR1 DISC1 DNAJC5 DTNBP1 EHD1 EHD2 MAPK14 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45
Entrez ID		5867	64145
HPRD ID		01541	15732
Ensembl ID		ENSG00000168118	ENSG00000131381
Uniprot IDs		A0A024R3U9 A0A087WYT5 P20338	A8K5H3 Q9H1K0
PDB IDs		1YU9 1Z0K 2BMD 2BME	1YZM 1Z0J 1Z0K
Enriched GO Terms of Interacting Partners?
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