PEX19 and PEX10

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (in vitro, in vivo)

		PEX19	PEX10
Description		peroxisomal biogenesis factor 19	peroxisomal biogenesis factor 10
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Brush Border Membrane Protein-containing Complex	Peroxisome Peroxisomal Membrane
	Molecular Function	Protein Binding Peroxisome Membrane Targeting Sequence Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Protein N-terminus Binding ATPase Binding	Protein Binding Metal Ion Binding
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Transmembrane Transport Chaperone-mediated Protein Folding Chaperone-mediated Protein Transport Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding	Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination
Pathways		ABC transporters in lipid homeostasis Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import	E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)	Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS			Body mass index ( 26426971) Non-obstructive azoospermia ( 22197933)
Interacting Genes		38 interacting genes: ABCD1 ABCD2 ABCD3 BCL2L11 CDC25A CDKN2A EIF1B F11R FKBP7 GSKIP IFNB1 IL23A IRF3 KIFAP3 MFSD5 NAT8L OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PSORS1C2 PXMP4 SLC25A17 SLC34A1 SMAD2 SRPK1 STK3 SUOX TMEM54 TXN2	10 interacting genes: CGRRF1 HNRNPD LIG4 MKRN3 PCGF6 PEX12 PEX19 PEX2 PEX5 UBE2I
Entrez ID		5824	5192
HPRD ID		02610	04175
Ensembl ID		ENSG00000162735	ENSG00000157911
Uniprot IDs		A0A0S2Z497 P40855	A0A024R068 A0A024R0A4 O60683
PDB IDs		2W85 2WL8 3AJB 3MK4 5LNF
Enriched GO Terms of Interacting Partners?
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