PVR and PLAT

Data Source:
BioGRID (affinity chromatography technology)

		PVR	PLAT
Description		PVR cell adhesion molecule	plasminogen activator, tissue type
Image
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Integral Component Of Membrane	Extracellular Region Extracellular Space Cytoplasm Cell Surface Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Virus Receptor Activity Protein Binding Signaling Receptor Activity Cell Adhesion Molecule Binding	Serine-type Endopeptidase Activity Signaling Receptor Binding Protein Binding Phosphoprotein Binding
	Biological Process	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Viral Entry Into Host Cell Regulation Of Immune Response Susceptibility To T Cell Mediated Cytotoxicity	Cellular Protein Modification Process Proteolysis Blood Coagulation Smooth Muscle Cell Migration Plasminogen Activation Fibrinolysis Negative Regulation Of Proteolysis Platelet-derived Growth Factor Receptor Signaling Pathway
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Nectin/Necl trans heterodimerization	Signaling by PDGF Dissolution of Fibrin Clot
Drugs		Sphingosine Myristic acid	Aminocaproic acid Iloprost Human C1-esterase inhibitor 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID Dexibuprofen Conestat alfa
Diseases
GWAS		Alzheimer's disease ( 24755620) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Mean platelet volume ( 32888494 27863252) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Platelet distribution width ( 32888494)	Blood protein levels ( 30072576) Plasma plasminogen activator levels ( 24578379) Systemic lupus erythematosus ( 28714469)
Interacting Genes		69 interacting genes: ADIPOQ ANKRD46 AP1M2 AQP10 BRICD5 C3orf52 CD226 CD47 CD96 CLDN19 CTXN3 CYB561A3 CYHR1 CYSRT1 DYNLT1 DYNLT3 EBP EDDM3B GPRC5D HHATL HOXA1 INSIG2 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-1 KRTAP3-3 KRTAP6-3 KRTAP9-3 MFSD11 NBPF19 NECTIN1 NECTIN3 NINJ1 NINJ2 NOTCH2NLA OLFM4 PGA4 PLA2G3 PLP2 PLPP6 RUSF1 SCD SFTPC SLC30A2 SLC35B4 SLC41A2 SMIM1 SNAP47 SYS1 TAS2R19 TIGIT TM6SF2 TMBIM6 TMEM147 TMEM229B TMEM54 TMEM65 TMEM79 TSPO VAMP5 VTN WNK1 ZDHHC15 ZDHHC22 ZFPL1	27 interacting genes: ANXA2 APP CALR CKAP4 CLEC3B F10 FGA FN1 GRIN1 HMGB1 KRT8 LAMA1 LAMA3 LRP1 LRP1B MAPK1 MAPK3 MTDH PDGFC PLAU PLG SERPINA5 SERPINE1 SERPING1 SERPINI1 SPARC VDAC1
Entrez ID		5817	5327
HPRD ID		01434	01419
Ensembl ID		ENSG00000073008	ENSG00000104368
Uniprot IDs		A0A0A0MSA9 A0A0C4DG49 A8K4I1 P15151	B4DN26 P00750
PDB IDs		1DGI 1NN8 3EPC 3EPD 3EPF 3J8F 3J9F 3UDW 3URO 4FQP 6ARQ 6ISC 6O3O	1A5H 1BDA 1PK2 1PML 1RTF 1TPG 1TPK 1TPM 1TPN 5BRR 5ZLZ
Enriched GO Terms of Interacting Partners?
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