PLAT and CKAP4

Data Source:
HPRD (in vitro, in vivo)

		PLAT	CKAP4
Description		plasminogen activator, tissue type	cytoskeleton associated protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cell Surface Collagen-containing Extracellular Matrix Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Lipid Droplet Cytosol Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane Nuclear Speck Azurophil Granule Membrane Specific Granule Membrane Cytoplasmic Ribonucleoprotein Granule Lamellar Body Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Signaling Receptor Binding Protein Binding Phosphoprotein Binding	RNA Binding
	Biological Process	Cellular Protein Modification Process Proteolysis Blood Coagulation Smooth Muscle Cell Migration Plasminogen Activation Fibrinolysis Negative Regulation Of Proteolysis Platelet-derived Growth Factor Receptor Signaling Pathway	Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Signaling by PDGF Dissolution of Fibrin Clot	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Surfactant metabolism Neutrophil degranulation Post-translational protein phosphorylation
Drugs		Aminocaproic acid Iloprost Human C1-esterase inhibitor 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID Dexibuprofen Conestat alfa
Diseases
GWAS		Blood protein levels ( 30072576) Plasma plasminogen activator levels ( 24578379) Systemic lupus erythematosus ( 28714469)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Metabolite levels ( 23823483) Refractive error ( 32231278)
Interacting Genes		27 interacting genes: ANXA2 APP CALR CKAP4 CLEC3B F10 FGA FN1 GRIN1 HMGB1 KRT8 LAMA1 LAMA3 LRP1 LRP1B MAPK1 MAPK3 MTDH PDGFC PLAU PLG SERPINA5 SERPINE1 SERPING1 SERPINI1 SPARC VDAC1	13 interacting genes: ASCC2 ATF4 DKK1 HAMP LINC01554 MLH1 MVP NDUFB7 NKX3-1 PLAT THOC7 TSNAX WASHC3
Entrez ID		5327	10970
HPRD ID		01419	16717
Ensembl ID		ENSG00000104368	ENSG00000136026
Uniprot IDs		B4DN26 P00750	A0A024RBH2 Q07065
PDB IDs		1A5H 1BDA 1PK2 1PML 1RTF 1TPG 1TPK 1TPM 1TPN 5BRR 5ZLZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?