SLAMF7 and CLK3

Data Source:
BioGRID (two hybrid)

		SLAMF7	CLK3
Description		SLAM family member 7	CDC like kinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Acrosomal Vesicle Nucleus Nucleoplasm Membrane Nuclear Speck Intermediate Filament Cytoskeleton
	Molecular Function	Identical Protein Binding	RNA Binding Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Adaptive Immune Response Cell Adhesion Natural Killer Cell Activation Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response	Protein Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Elotuzumab	K-00546 ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate Fostamatinib
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) IgM levels ( 28628107) Inflammatory bowel disease ( 23128233) Microalbuminuria ( 26631737) Multiple sclerosis ( 24076602)	Bladder cancer ( 25281661) Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level) ( 27702941) Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Celiac disease ( 22057235) Coffee consumption (cups per day) ( 31837886) Craniofacial microsomia ( 26853712)
Interacting Genes		4 interacting genes: CLK3 MAK SH2D1A TRIB2	40 interacting genes: APP CHERP CLASRP CLK2 DDIT4L HOXB6 HOXB7 HOXC4 INCA1 KRTAP10-3 LNX1 NEDD4 NKAPL NXF1 OAS2 PRMT5 RBMX RBMY1A1 RBMY1F RNF8 RNPS1 RSRP1 SAG SDCBP SH2B2 SLAMF7 SNIP1 SNRNP35 SRPK2 SRSF10 SRSF3 SRSF8 SUV39H1 TINF2 TRA2B YWHAG ZNF263 ZNF473 ZNF777 ZNF835
Entrez ID		57823	1198
HPRD ID		09432	04290
Ensembl ID		ENSG00000026751	ENSG00000179335
Uniprot IDs		B4DVL7 B4DW98 Q9NQ25	B3KRI8 P49761
PDB IDs			2EU9 2EXE 2WU6 2WU7 3RAW 6FT7 6FYP 6FYR 6KHF 6RCT 6YTW 6YTY 6YU1 6Z2V 6Z51 6Z52 6Z53 6Z54 6Z55
Enriched GO Terms of Interacting Partners?
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