SFMBT2 and LYPLA1

Data Source:
BioGRID (two hybrid)

		SFMBT2	LYPLA1
Description		Scm like with four mbt domains 2	lysophospholipase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Aggresome Nuclear Body Nuclear Speck Intracellular Membrane-bounded Organelle	Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Nuclear Membrane Extracellular Exosome
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Binding	Phospholipase Activity Lysophospholipase Activity Protein Binding Palmitoyl-(protein) Hydrolase Activity Lipase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated	Protein Depalmitoylation Fatty Acid Metabolic Process Protein Phosphopantetheinylation Negative Regulation Of Golgi To Plasma Membrane Protein Transport Regulation Of Nitric-oxide Synthase Activity
Pathways			eNOS activation RAS processing
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 31036433) Fasting blood insulin (BMI interaction) ( 22581228) Femoral neck bone mineral density ( 32239398) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Monoclonal gammopathy of undetermined significance ( 30737484)	Itch intensity from mosquito bite adjusted by bite size ( 28199695) Pelvic organ prolapse (moderate/severe) ( 26545240) Urinary albumin-to-creatinine ratio ( 26631737) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
Interacting Genes		11 interacting genes: CLK1 L3MBTL3 LYPLA1 PHC1 SCMH1 SCML1 SCML2 SIAH1 SLF2 TFAP4 UBE2O	3 interacting genes: ANXA2 GOLGA2 SFMBT2
Entrez ID		57713	10434
HPRD ID		18853	07063
Ensembl ID		ENSG00000198879	ENSG00000120992
Uniprot IDs		Q5VUG0	A0A087X1K9 B4DP64 O75608 Q6IAQ1
PDB IDs		1WJR	1FJ2 5SYM 6QGN 6QGO 6QGQ 6QGS
Enriched GO Terms of Interacting Partners?
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