ADGRB3 and SLC7A1

Data Source:
BioGRID (two hybrid)

		ADGRB3	SLC7A1
Description		adhesion G protein-coupled receptor B3	solute carrier family 7 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Synaptic Cleft Postsynapse	Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Protein-containing Complex
	Molecular Function	G Protein-coupled Receptor Activity GTPase Activator Activity Protein Binding	L-ornithine Transmembrane Transporter Activity L-histidine Transmembrane Transporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transporter Activity Arginine Transmembrane Transporter Activity L-lysine Transmembrane Transporter Activity L-arginine Transmembrane Transporter Activity
	Biological Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Myoblast Fusion Neuron Remodeling Negative Regulation Of Angiogenesis Positive Regulation Of GTPase Activity Regulation Of Dendrite Morphogenesis Positive Regulation Of Synapse Assembly Motor Learning Maintenance Of Synapse Structure	Amino Acid Transport L-amino Acid Transport Lysine Transport Ornithine Transport Positive Regulation Of T Cell Proliferation Amino Acid Import Across Plasma Membrane L-arginine Import Across Plasma Membrane Transport Across Blood-brain Barrier L-ornithine Transmembrane Transport L-lysine Transmembrane Transport L-histidine Import Across Plasma Membrane Arginine Transmembrane Transport Basic Amino Acid Transmembrane Transport
Pathways			Amino acid transport across the plasma membrane
Drugs			L-Lysine Arginine Ornithine
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) Negative urgency ( 30718321) Sensory peripheral neuropathy in microtubule targeting agent-treated breast cancer ( 32562552)	Blood osmolality (transformed sodium) ( 28360221) Diastolic blood pressure ( 27841878) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		8 interacting genes: C1QL3 ELMO1 GPATCH11 GPR37L1 MUC1 SLC7A1 SNTA1 TLCD4	57 interacting genes: ADGRB3 APOA2 APP AQP6 ATP6V0C C8A CBLIF CCL4 CCL4L2 CD40 CD79A CDIPT CERS4 CMTM2 COMT CREB3L1 EMC6 FAM241B FATE1 FCER1G GALNT15 GET1 GLB1 GPR152 HERPUD2 LEPROT LEPROTL1 LMNA MFF MGST3 MS4A13 NUCB2 ORMDL3 PDCD1LG2 PNLIPRP1 PSCA PTPN9 RNF144A SACM1L SCN3B SEC23A SLC10A6 SLC18A2 SLC30A2 SLC39A2 SLC39A9 SLC52A1 SMCO4 ST6GAL2 STIM1 TMBIM6 TMEM14A TMEM19 TMEM237 TRARG1 TSPO2 YIPF4
Entrez ID		577	6541
HPRD ID		04064	00091
Ensembl ID		ENSG00000135298	ENSG00000139514
Uniprot IDs		O60242	A0A024RDQ9 P30825
PDB IDs		4DLO
Enriched GO Terms of Interacting Partners?
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