RNF213 and UBXN11

Data Source:
BioGRID (two hybrid)

		RNF213	UBXN11
Description		ring finger protein 213	UBX domain protein 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Membrane	Cytoplasm Cytoskeleton
	Molecular Function	Ubiquitin-protein Transferase Activity ATPase Activity Metal Ion Binding	Protein Binding Ubiquitin Binding
	Biological Process	Protein Polyubiquitination Angiogenesis Sprouting Angiogenesis Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Homooligomerization Protein Autoubiquitination Negative Regulation Of Non-canonical Wnt Signaling Pathway	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Suppression of apoptosis Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Coronary artery disease ( 33020668) Lipoprotein-associated phospholipase A2 activity change in response to statin therapy ( 23118302) Migraine ( 27182965 27322543) Moyamoya disease ( 21048783 29273593)	Monocyte percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 32888494)
Interacting Genes		12 interacting genes: GOLGA2 KRT40 MTDH PLAC9 REL SUMO2 TRIM23 TRIM27 TRIP6 UBE2D2 UBE2L3 UBXN11	34 interacting genes: C14orf119 CFAP206 EIF4E EIF4E2 ENKD1 HGS IL16 LENG1 NEK6 PPM1K PRKAA1 PRKAB2 PRPF18 PRPF31 PRR35 PSMA1 RHOBTB3 RND1 RND2 RND3 RNF213 SCNM1 SH2D4A SNRPB TCEANC TLE5 TRAF2 TTC23 USHBP1 VCP VPS9D1 WDR25 ZFYVE9 ZGPAT
Entrez ID		57674	91544
HPRD ID		10716	10245
Ensembl ID		ENSG00000173821	ENSG00000158062
Uniprot IDs		A0A0A0MTC1 A0A0A0MTR7 Q63HN8	Q5T124
PDB IDs
Enriched GO Terms of Interacting Partners?
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