CALCOCO1 and CRYBA2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CALCOCO1	CRYBA2
Description		calcium binding and coiled-coil domain 1	crystallin beta A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Intracellular Membrane-bounded Organelle	Cellular_component
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Nuclear Receptor Coactivator Activity Sequence-specific DNA Binding Metal Ion Binding Armadillo Repeat Domain Binding	Molecular_function Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of Gene Expression Wnt Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Lens Development In Camera-type Eye Visual Perception Biological_process
Pathways
Drugs
Diseases
GWAS		Panic disorder ( 19165232) Toenail selenium levels ( 25343990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Height ( 31562340 18391951) Macular thickness ( 30535121) Neutrophil percentage of white cells ( 32888494) Systolic blood pressure ( 28234671) Type 2 diabetes (adjusted for BMI) ( 30297969)
Interacting Genes		35 interacting genes: APP APTX ARNT BFSP2 CEP19 CREBBP CRYBA2 CTNNBL1 CWF19L2 CYTH3 DUSP13 ENKD1 EP300 FAM161A FOSL1 GABARAPL1 GABARAPL2 GRIK2 IPP ISOC1 KRT15 MAPK1 MYH6 NDC80 NEDD4 PCBD1 POLR2A PRKAA2 RNF8 SH3GL3 SMURF1 SRPK2 TBC1D15 TBC1D17 ZMAT2	27 interacting genes: ANAPC11 ARID5A BPIFA1 C10orf55 C22orf39 CALCOCO1 CCDC33 CRYBB1 CRYBB2 CRYBB3 CTDSP1 CYSRT1 FHL3 FHL5 KRTAP11-1 KRTAP13-3 KRTAP7-1 LASP1 NFKBID OXER1 PRR22 RUSC1 TRAF2 TRIP13 UNKL VAC14 YPEL3
Entrez ID		57658	1412
HPRD ID		13868	02905
Ensembl ID		ENSG00000012822	ENSG00000163499
Uniprot IDs		A0A024RAZ1 Q9P1Z2	A0A024R429 P53672
PDB IDs
Enriched GO Terms of Interacting Partners?
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