HHATL and CISD2

Data Source:
BioGRID (two hybrid)

		HHATL	CISD2
Description		hedgehog acyltransferase like	CDGSH iron sulfur domain 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding Transferase Activity, Transferring Acyl Groups	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Negative Regulation Of N-terminal Protein Palmitoylation	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy
Pathways
Drugs
Diseases			Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS			Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)
Interacting Genes		20 interacting genes: ADRA1A AGTR1 AMIGO1 BDKRB1 C4orf3 CACNA1A CISD2 CPLX4 CXCL16 ERGIC3 FAM209A FKBP7 FNDC9 GPR152 GPX8 MILR1 MUC1 PVR SUSD3 TMX2	58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6
Entrez ID		57467	493856
HPRD ID		12166	17413
Ensembl ID		ENSG00000010282	ENSG00000145354
Uniprot IDs		A0A024R2R3 Q5QTR4 Q9HCP6	Q8N5K1
PDB IDs			3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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