TTYH1 and CCR9

Data Source:
BioGRID (two hybrid)

		TTYH1	CCR9
Description		tweety family member 1	C-C motif chemokine receptor 9
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Smooth Endoplasmic Reticulum Membrane Filopodium Membrane Filopodium Tip Chloride Channel Complex Synapse	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface
	Molecular Function	Intracellular Calcium Activated Chloride Channel Activity Chloride Channel Activity Iron Ion Transmembrane Transporter Activity Calcium Ion Binding Protein Binding Volume-sensitive Chloride Channel Activity	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Mitotic Cell Cycle Chloride Transport Iron Ion Transport Cell-substrate Adhesion Ion Transmembrane Transport Iron Ion Transmembrane Transport Filopodium Assembly Cell-cell Adhesion Chloride Transmembrane Transport	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs			Vercirnon
Diseases
GWAS		Blood trace element (Se levels) ( 23720494) Idiopathic pulmonary fibrosis ( 29066090)	Celiac disease ( 20190752) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)
Interacting Genes		5 interacting genes: CCR9 DRD2 GPR37 HTR6 TMEM60	19 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TRPM4 TSPAN7 TTYH1 YWHAE
Entrez ID		57348	10803
HPRD ID		12043	09200
Ensembl ID		ENSG00000167614	ENSG00000173585
Uniprot IDs		Q9H313	B2R734 P51686
PDB IDs			5LWE
Enriched GO Terms of Interacting Partners?
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