PLAAT1 and ZIC1

Data Source:
BioGRID (two hybrid)

		PLAAT1	ZIC1
Description		phospholipase A and acyltransferase 1	Zic family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Lumen Cytoplasm Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Phospholipase A2 Activity Protein Binding O-acyltransferase Activity Phospholipase A1 Activity N-acyltransferase Activity Phosphatidylserine 1-acylhydrolase Activity 1-acyl-2-lysophosphatidylserine Acylhydrolase Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Lipid Catabolic Process Phosphatidylcholine Metabolic Process N-acylphosphatidylethanolamine Metabolic Process	Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Central Nervous System Development Brain Development Regulation Of Smoothened Signaling Pathway Cell Differentiation Positive Regulation Of Protein Import Into Nucleus Inner Ear Morphogenesis Positive Regulation Of Transcription, DNA-templated
Pathways		Acyl chain remodelling of PE
Drugs
Diseases
GWAS			Adult body size ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chin dimples ( 27182965) Cortical surface area (MOSTest) ( 32665545) Daytime sleep phenotypes ( 27126917) Monobrow ( 27182965) Multiple sclerosis ( 19010793) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		7 interacting genes: APP CCDC103 GPANK1 HGS TLX3 UBQLN1 ZIC1	71 interacting genes: ABHD11 ANKRD10 ARID5A ATP23 BBS4 C11orf1 CDPF1 CRX CYSRT1 DAPL1 EEF1AKMT3 FAM168B FOXH1 GLI1 GLI2 GLI3 INTS11 KLHL26 KRT31 KRT34 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-5 KRTAP19-7 KRTAP21-2 KRTAP22-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LITAF MAGED1 METTL27 MGAT5B NFKBID OIP5 OXER1 PATZ1 PEF1 PLAAT1 PLSCR3 RBPMS REL RFC2 RNF144B RUSC1 SMAD4 SMUG1 SPAG8 SPATS1 SUFU TBX19 TEPSIN TLE5 TRAF1 TRIP6 TSC1 UBE2I UFSP1 WWOX YPEL3 ZNF34 ZNF474 ZNF620
Entrez ID		57110	7545
HPRD ID		07577	02718
Ensembl ID		ENSG00000127252	ENSG00000152977
Uniprot IDs		Q9HDD0	Q15915
PDB IDs
Enriched GO Terms of Interacting Partners?
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