CYSLTR2 and PCDH9

Data Source:
BioGRID (two hybrid)

		CYSLTR2	PCDH9
Description		cysteinyl leukotriene receptor 2	protocadherin 9
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Plasma Membrane Integral Component Of Plasma Membrane	Integral Component Of Plasma Membrane Growth Cone Cell-cell Contact Zone
	Molecular Function	Cysteinyl Leukotriene Receptor Activity Leukotriene Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity	Calcium Ion Binding
	Biological Process	Immune Response G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Leukotriene Signaling Pathway	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Forebrain Development
Pathways		Glucagon signaling in metabolic regulation Leukotriene receptors G alpha (q) signalling events G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production LTC4-CYSLTR mediated IL4 production
Drugs		Nedocromil Leukotriene C4 Leukotriene D4
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382) Systemic juvenile idiopathic arthritis ( 27927641)	Adult body size ( 32376654) Blood protein levels ( 30072576) Body size at age 10 ( 32376654) Chronotype ( 30696823) Current cigarettes per day in chronic obstructive pulmonary disease ( 29631575) Dental caries ( 23064961) Feeling nervous ( 29500382) Forced expiratory volume in 1 second (occupational environmental exposures interaction) ( 25979521) General factor of neuroticism ( 30867560) Insomnia ( 29520036) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Latent naming speed ( 30995994) Major depressive disorder ( 27479909) Male fertility ( 22633400) Metabolite levels ( 23823483) Obesity ( 21552555) Photic sneeze reflex ( 27182965) Postoperative survival time in hepatocellular carcinoma ( 30945673 30945699) Pulmonary function decline ( 22424883) Recalcitrant atopic dermatitis ( 25935106) Refractive error ( 32231278) Response to platinum-based chemotherapy (cisplatin) ( 21844884) Sense of smell ( 26632684) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		19 interacting genes: ATP5MC2 DBI ENO1 GNAS GRIK1 HSP90B1 KRTAP1-1 LNX1 MTUS2 NCKIPSD PCDH9 PCMT1 RNASEK RNF144A RTN4 SVOP TTC19 YIPF6 YWHAE	2 interacting genes: CYSLTR2 MEOX2
Entrez ID		57105	5101
HPRD ID		09293	04661
Ensembl ID		ENSG00000152207	ENSG00000184226
Uniprot IDs		A4ZKH2 Q5KU17 Q9NS75	A7E2D9 B7ZM79 Q5VT82 Q9HC56 X5D7N0
PDB IDs			2EE0
Enriched GO Terms of Interacting Partners?
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