XAB2 and DHX16

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		XAB2	DHX16
Description		XPA binding protein 2	DEAH-box helicase 16
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Membrane Intracellular Membrane-bounded Organelle U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex U2-type Precatalytic Spliceosome
	Molecular Function	Protein Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATPase Activity
	Biological Process	Generation Of Catalytic Spliceosome For First Transesterification Step MRNA Splicing, Via Spliceosome Blastocyst Development Transcription-coupled Nucleotide-excision Repair Transcription, DNA-templated Cerebral Cortex Development	MRNA Splicing, Via Spliceosome RNA Splicing
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269)
Interacting Genes		17 interacting genes: CACHD1 DHX16 ERCC6 ERCC8 GLIS2 ILF3 ISY1 MIR106B MIR34B MIRLET7E MIRLET7G MIRLET7I POLR2A PPIE SMAD9 SUMO2 XPA	10 interacting genes: APP APPBP2 COIL CSNK2A1 ESS2 HOMEZ MEGF10 SNRNP27 SNRNP40 XAB2
Entrez ID		56949	8449
HPRD ID		18306	04555
Ensembl ID		ENSG00000076924	ENSG00000204560
Uniprot IDs		Q9HCS7	A0A1U9X7L7 B4DZ28 O60231 Q5SQH4
PDB IDs		5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P	5Z56 5Z57 5Z58 6FF7
Enriched GO Terms of Interacting Partners?
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