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MAP3K7CL and GPS2
Data Source:
HPRD
(two hybrid)
MAP3K7CL
GPS2
Description
MAP3K7 C-terminal like
G protein pathway suppressor 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytosol
Nucleus
Nucleoplasm
Mitochondrion
Cytosol
Transcription Repressor Complex
Molecular Function
Protein Binding
Transcription Coactivator Activity
Transcription Corepressor Activity
GTPase Inhibitor Activity
Protein Binding
Cyclin Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Inactivation Of MAPK Activity
JNK Cascade
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Cholesterol Efflux
Viral Process
Regulation Of Lipid Metabolic Process
B Cell Differentiation
Negative Regulation Of Toll-like Receptor Signaling Pathway
Negative Regulation Of GTPase Activity
Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
Regulation Of Fat Cell Differentiation
Negative Regulation Of Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of JNK Cascade
Negative Regulation Of Inflammatory Response
Negative Regulation Of B Cell Receptor Signaling Pathway
Response To Mitochondrial Depolarisation
Negative Regulation Of Protein K63-linked Ubiquitination
Pathways
PPARA activates gene expression
HDACs deacetylate histones
Loss of MECP2 binding ability to the NCoR/SMRT complex
Regulation of MECP2 expression and activity
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
HCMV Early Events
Drugs
Diseases
GWAS
Coronary artery disease (
29212778
33020668
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) (
30920136
)
Gamma glutamyl transferase levels (
29403010
)
Ventricular ectopy (
29618737
)
White blood cell count (
32888494
)
Interacting Genes
9 interacting genes:
AK8
CISH
DDIT4L
GPS2
KRT31
KRT34
REL
TAB3
USF1
53 interacting genes:
AKAP8L
ATF4
ATF5
BAG4
BRME1
C19orf54
CCNA1
CHD3
CNOT2
CYSRT1
DAZAP2
EP300
FAM168B
FHL5
GOLGA2
HDAC1
HDAC3
HNRNPH1
HOXA1
INTS11
KRT27
KRT31
KRT34
KRT36
KRTAP11-1
KRTAP13-2
KRTAP3-1
KRTAP3-3
KRTAP6-1
KRTAP6-2
KRTAP6-3
MAP3K7CL
NCOR1
NDOR1
NR0B2
OIP5
PBK
POU2AF1
PRMT6
PRR22
RBPMS
SESTD1
SETDB1
SMUG1
SPDL1
TBL1X
TBL1XR1
TFIP11
TP53
TP53BP2
TRIP6
UBTD2
VPS37C
Entrez ID
56911
2874
HPRD ID
10764
11878
Ensembl ID
ENSG00000156265
ENSG00000132522
Uniprot IDs
B0EVZ6
B0EVZ7
B0EVZ8
B4DFW0
P57077
Q13227
PDB IDs
2L5G
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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