DPYSL5 and FES

  • Data Source:
  • HPRD (in vitro, in vivo)

DPYSL5

FES

Description dihydropyrimidinase like 5 FES proto-oncogene, tyrosine kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cortical surface area (min-P) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Cortical thickness (MOSTest) ( 32665545)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Fasting blood glucose ( 22581228)
  • Fasting blood glucose (BMI interaction) ( 22581228)
  • Obesity-related traits ( 23251661)
  • Reflection (response to stress) ( 30886212)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Urate levels ( 31578528)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
  • White blood cell count ( 32888494)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Birth weight ( 31043758 27680694)
  • Blood pressure ( 21909110)
  • Brain morphology (MOSTest) ( 32665545)
  • Coffee consumption ( 31046077)
  • Coronary artery disease ( 32469254 29212778 30104761 26343387 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Daytime sleep phenotypes ( 27126917)
  • Diastolic blood pressure ( 27841878 21909115 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Hypertension ( 31879980 21909115)
  • Ischemic stroke ( 29531354)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Myocardial infarction ( 26343387)
  • Number of sexual partners ( 30643258)
  • Offspring birth weight ( 31043758)
  • Parental lifespan ( 30642433)
  • Pulse pressure ( 27841878 30578418)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Schizophrenia ( 25056061 29483656 30285260)
  • Stroke ( 29531354)
  • Systolic blood pressure ( 26390057 28135244 27841878 21909115 28739976 27618452 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 9 interacting genes: APPL1 CFAP161 DARS2 DPYS DPYSL2 DPYSL3 DPYSL4 FES HSPA5 40 interacting genes: APP AR BCAR1 BCR CSF2RB DOK1 DPYSL5 EGFR ERBB2 ERBB3 ERBB4 FKBP4 FKBP5 GAB1 HSH2D HSPA4 IL4R IRS1 IRS2 JAK1 JAK2 JAK3 KIT MDFI MET NEDD4 PDE4DIP PIK3R1 PLXNA1 POT1 PPID PTGES3 RASA1 RASA3 SMURF1 STAT3 TERF1 TRIM28 ZNF746 ZNF775
Entrez ID 56896 2242
HPRD ID 10522 01814
Ensembl ID ENSG00000157851 ENSG00000182511
Uniprot IDs Q9BPU6 A0A024RC92 P07332
PDB IDs 4B90 4B91 4B92 1WQU 2DCR 3BKB 3CBL 3CD3 4DYL 4E93 6JMF
Enriched GO Terms of Interacting Partners?
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