EIF4ENIF1 and TCHP

Data Source:
BioGRID (two hybrid)

		EIF4ENIF1	TCHP
Description		eukaryotic translation initiation factor 4E nuclear import factor 1	trichoplein keratin filament binding
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle	Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Desmosome Keratin Filament Apical Cortex
	Molecular Function	RNA Binding MRNA Binding Nuclear Export Signal Receptor Activity Protein Binding Kinase Binding	Protein Binding
	Biological Process	Protein Import Into Nucleus Negative Regulation Of Translation Stem Cell Population Maintenance Gene Silencing By RNA P-body Assembly Negative Regulation Of Neuron Differentiation MRNA Stabilization Nuclear Export Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of MiRNA Mediated Inhibition Of Translation	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Myocardial infarction ( 30226566) Platelet count ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		27 interacting genes: ATXN1 CDK6 CFAP206 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 L3MBTL2 MGAT5B OIP5 PRR20A PRR20B PRR20C PRR20D PRR20E SMAD3 SPAG5 TCHP TTC19 TXLNA USP2	52 interacting genes: ATPAF2 BCAS2 C21orf91 CBY2 CCDC125 CCDC13 CCDC172 CCDC85B CDR2 CDR2L DMAP1 DYDC1 EIF4ENIF1 HOOK2 ID2 IFFO1 IKZF3 KCTD17 KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT32 KRT34 KRT35 KRT40 KRT5 KRT6A KRT75 KRT8 MIIP MIPOL1 MKRN3 MTUS2 NAB2 NDOR1 NME7 NUP54 PRDM16 PSMB5 RABGEF1 RUSC1 TEX11 TRIM27 TRIM54 USHBP1 VIM WWOX ZIM2
Entrez ID		56478	84260
HPRD ID		10456	14403
Ensembl ID		ENSG00000184708	ENSG00000139437
Uniprot IDs		A0A024R1K0 Q9NRA8	A0A024RBM9 Q9BT92
PDB IDs		5ANR 6F9W 6X2R
Enriched GO Terms of Interacting Partners?
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