TEX14 and LMO4

Data Source:
BioGRID (two hybrid)

		TEX14	LMO4
Description		testis expressed 14, intercellular bridge forming factor	LIM domain only 4
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GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Cytoplasm Midbody Intercellular Bridge Extracellular Exosome	Transcription Regulator Complex Cell Leading Edge RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Protein Kinase Binding	Protein Binding Transcription Factor Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Mitotic Spindle Assembly Checkpoint Male Meiotic Nuclear Division Attachment Of Spindle Microtubules To Kinetochore Negative Regulation Of Protein Binding Negative Regulation Of Cytokinesis Intercellular Bridge Organization Cell Division Mitotic Sister Chromatid Separation Cellular Response To Leukemia Inhibitory Factor	Neural Tube Closure Ventricular Septum Development Ventral Spinal Cord Interneuron Differentiation Spinal Cord Motor Neuron Differentiation Spinal Cord Association Neuron Differentiation Regulation Of Cell Migration Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Kinase Activity Regulation Of Cell Fate Specification Positive Regulation Of Transcription By RNA Polymerase II Thymus Development Regulation Of Cell Activation
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Cognitive function ( 25644384) Estimated glomerular filtration rate ( 31152163) Iron status biomarkers (ferritin levels) ( 25352340) Neutrophil count ( 32888494) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278) Testicular germ cell tumor ( 25877299 28604728 28604732 23666239 23666240) Type 2 diabetes ( 30054458) White blood cell count ( 32888494)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Breast cancer ( 27354352) Eosinophil counts ( 29403010) Gait rhythm ( 26219847) Glaucoma (primary open-angle) ( 29891935) Photic sneeze reflex ( 27182965) Prostate-specific antigen levels ( 28139693) Response to TNF antagonist treatment ( 18615156) Resting heart rate ( 27798624) White blood cell count (basophil) ( 29403010) White blood cell types ( 21738478)
Interacting Genes		5 interacting genes: CEP55 DDIT4L LHX3 LMO4 MEOX2	130 interacting genes: AARD ABI2 ADAMTSL4 AMOT AMOTL2 ARNT2 BANP BBS2 BCAS2 BIRC7 BRCA1 C12orf40 CALCOCO2 CCDC102B CCDC120 CEP170P1 COG6 CRNN CRYBB2 CSNK2B CTBP2 CYSRT1 DDB1 DEAF1 DES ECM1 ERCC6L EXOSC8 FAM228A FHL3 GABPB1 GADD45A GOLGA2 GOLGA6L9 GRHL2 GSK3B HELT HGS HSF2BP ID3 IKZF1 IKZF3 ITSN1 KANK2 KATNBL1 KIAA1958 KIF3B KPNA1 KRT15 KRT31 KRT33B KRT34 KRT38 KRT39 KRT40 KRT74 KRT75 KRT76 KRTAP11-1 KRTAP3-1 KYNU L3MBTL3 LASP1 LDB1 LDB2 LMO2 LZTS1 MCCD1 MERTK METTL27 MID2 MTA1 MTUS2 MYOD1 MYOZ3 N4BP3 NFKBID NFYC NHLH1 NME4 NONO NRF1 PDE4DIP PELO PER2 PITPNB PLK1 PPARG PPP1R32 QRICH1 RBAK RBBP8 RBPMS RCN1 RNF8 ROPN1 RPS6KA6 RSPH6A SEC24D SLC15A2 SMAD4 SMAD9 STAT5B SUOX TCF21 TCF4 TEX14 TFIP11 TINAGL1 TLE5 TNFSF11 TP53BP2 TRAF5 TRIM27 TRIM54 TSEN15 TTLL7 UBQLN2 VMAC VPS52 WASHC1 ZBTB43 ZMYND12 ZNF135 ZNF202 ZNF213 ZNF397 ZNF410 ZNF467 ZNF675
Entrez ID		56155	8543
HPRD ID		12046	09122
Ensembl ID		ENSG00000121101	ENSG00000143013
Uniprot IDs		Q8IWB6	P61968
PDB IDs		3WUT 3WUU	2L4Z
Enriched GO Terms of Interacting Partners?
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