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NXF2 and NUP214
Data Source:
HPRD
(in vitro)
NXF2
NUP214
Description
nuclear RNA export factor 2
nucleoporin 214
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nuclear RNA Export Factor Complex
Nuclear Pore
Nucleoplasm
Cytosol
Host Cell
Cytoplasmic Side Of Nuclear Pore
Molecular Function
RNA Binding
Protein Binding
Nuclear Export Signal Receptor Activity
Protein Binding
Nuclear Localization Sequence Binding
Structural Constituent Of Nuclear Pore
Biological Process
MRNA Export From Nucleus
Multicellular Organism Development
Poly(A)+ MRNA Export From Nucleus
RNA Transport
Mitotic Cell Cycle
Regulation Of Glycolytic Process
RNA Export From Nucleus
MRNA Export From Nucleus
TRNA Export From Nucleus
Protein Import Into Nucleus
Protein Export From Nucleus
Viral Process
Protein Sumoylation
Viral Transcription
Regulation Of MRNA Stability
Regulation Of Nucleocytoplasmic Transport
Regulation Of Cell Cycle
Regulation Of Gene Silencing By MiRNA
Intracellular Transport Of Virus
Regulation Of Cellular Response To Heat
Pathways
Transport of Mature mRNA derived from an Intron-Containing Transcript
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
HuR (ELAVL1) binds and stabilizes mRNA
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Drugs
Diseases
GWAS
Aspartate aminotransferase levels (
31219225
)
Interacting Genes
11 interacting genes:
APEX1
APP
HNRNPUL1
MAP1A
MAP1B
NUP153
NUP214
NUP62
NXF1
NXT1
NXT2
20 interacting genes:
APC
CLEC4G
DDX19B
IPO5
NFX1
NUP107
NUP42
NUP62
NUP88
NXF1
NXF2
SMAD2
SMAD3
SMAD4
SUMO2
TNPO1
XPO1
XPO5
XPOT
ZFP36
Entrez ID
56001
8021
HPRD ID
02260
00258
Ensembl ID
ENSG00000269405
ENSG00000126883
Uniprot IDs
Q9GZY0
B7ZAV2
P35658
PDB IDs
2OIT
3FHC
3FMO
3FMP
5DIS
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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