WSB2 and CSF3R

Data Source:
BioGRID (affinity chromatography technology, imaging technique, protein complementation assay)

		WSB2	CSF3R
Description		WD repeat and SOCS box containing 2	colony stimulating factor 3 receptor
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Receptor Complex
	Molecular Function		Cytokine Receptor Activity Protein Binding Cytokine Binding Signaling Receptor Activity Granulocyte Colony-stimulating Factor Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Post-translational Protein Modification	Defense Response Cell Adhesion Signal Transduction Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Regulation Of Myeloid Cell Differentiation Amelogenesis
Pathways		Neddylation	Other interleukin signaling Transcriptional regulation of granulopoiesis
Drugs			Pegfilgrastim Filgrastim FavId Lenograstim Lipegfilgrastim
Diseases
GWAS		Red blood cell count ( 32888494)	Basophil count ( 32888494) Cerebrospinal fluid p-tau levels ( 29274321) Cerebrospinal fluid t-tau levels ( 29274321) Eosinophil percentage of white cells ( 32888494) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Iron status biomarkers (total iron binding capacity) ( 28334935) Lymphocyte percentage of white cells ( 32888494 27863252) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 29403010 32888494 27863252)
Interacting Genes		3 interacting genes: CSF3R EZH2 RPN1	19 interacting genes: CISH CSF3 ELANE FTH1 GRB2 HCK INPP5D JAK1 JAK2 LCK LYN PLA2G1B PTPN11 SHC1 SOCS3 STAT3 SYK WSB1 WSB2
Entrez ID		55884	1441
HPRD ID		18305	00737
Ensembl ID		ENSG00000176871	ENSG00000119535
Uniprot IDs		Q9NYS7	Q99062
PDB IDs			1AZ7 2D9Q
Enriched GO Terms of Interacting Partners?
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