EXOC1 and CEP295

Data Source:
BioGRID (two hybrid)

		EXOC1	CEP295
Description		exocyst complex component 1	centrosomal protein 295
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Plasma Membrane Mitotic Spindle Microtubule
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding	Microtubule Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Viral Process Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Defense Response To Virus	Centriole Replication Positive Regulation Of Centrosome Duplication Regulation Of Centriole Replication Positive Regulation Of Protein Acetylation Positive Regulation Of Centriole Elongation Positive Regulation Of Establishment Of Protein Localization
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Urinary albumin excretion ( 32277301) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Leukocyte telomere length ( 32109421)
Interacting Genes		30 interacting genes: ATG14 CCDC88A CCDC93 CCHCR1 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 NUP54 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SNAPIN SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO	1 interacting genes: EXOC1
Entrez ID		55763	85459
HPRD ID		07615	11159
Ensembl ID		ENSG00000090989	ENSG00000166004
Uniprot IDs		A0A024RDA1 A1LT29 Q9NV70	Q9C0D2
PDB IDs
Enriched GO Terms of Interacting Partners?
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