FAM222B and TTLL12

Data Source:
BioGRID (two hybrid)

		FAM222B	TTLL12
Description		family with sequence similarity 222 member B	tubulin tyrosine ligase like 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleus Cytoplasm Microtubule Organizing Center Spindle Midbody
	Molecular Function	Protein Binding	Tubulin-tyrosine Ligase Activity Protein Binding ATP Binding Tubulin Binding Histone-lysine N-methyltransferase Activity H4K20me3 Modified Histone Binding
	Biological Process		Regulation Of Mitotic Cell Cycle Protein Phosphopantetheinylation Histone Lysine Methylation Innate Immune Response Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Histone H4-K20 Methylation
Pathways			Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS		Estimated glomerular filtration rate reduction (30%) ( 30955190) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Red blood cell count ( 32888494) Red cell distribution width ( 27863252)	Molar-incisor hypomineralization ( 23918034) Monocyte count ( 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		35 interacting genes: ANKRD10 BAG4 BANP BPIFA1 C10orf55 C19orf54 CDCA4 CNFN FAM168B FHL3 FOSB HYI INTS11 KRTAP11-1 KRTAP26-1 KRTAP3-1 LRRC61 OIP5 PDLIM4 PFDN5 PLA2G10 PRR20A PRR20B PRR20C PRR20D PRR20E RUNX1 SOHLH1 TRIP6 TSC1 TTLL12 UBQLN2 UFSP1 WWOX ZMYND12	7 interacting genes: CSNK2A2 DNAJB1 EEF1A1 EEF1A2 FAM222B PRR35 SUMO2
Entrez ID		55731	23170
HPRD ID		07693	13782
Ensembl ID		ENSG00000173065	ENSG00000100304
Uniprot IDs		A0A024QZ60 B3KQ88 B3KTH5 B4DRX9 Q8WU58	A0A024R4U3 Q14166
PDB IDs
Enriched GO Terms of Interacting Partners?
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