GPATCH2L and PRDM14

Data Source:
BioGRID (two hybrid, two hybrid)

		GPATCH2L	PRDM14
Description		G-patch domain containing 2 like	PR/SET domain 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Metal Ion Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Germ Cell Development Embryo Implantation Fertilization Regulation Of Gene Expression Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Somatic Stem Cell Population Maintenance Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance
Pathways			Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Red blood cell count ( 32888494)	Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		47 interacting genes: APP BATF3 CARD10 CCDC33 CEP70 CSNK2A1 CYSRT1 DIP2A HSF2BP KDM1A KRT40 KRTAP10-9 KRTAP4-12 LMO1 LMO3 LZTS2 MAB21L3 MDFI MEOX2 NAA10 NDUFB7 PDLIM7 PLAGL2 PNMA2 PRDM14 PRMT1 PRMT8 PSME3 RBM11 RBPMS SUV39H1 THAP1 TLE5 TRIB3 TRIM41 TSPYL1 TULP3 ZBTB48 ZBTB8A ZNF165 ZNF263 ZNF398 ZNF408 ZNF473 ZNF526 ZNF547 ZNF837	67 interacting genes: ABI2 AKAP9 AQP1 ATPAF2 BAG4 BAHD1 BCAR3 BEX2 CARD10 CASP8 CBFA2T2 CDCA7L CHEK2 CREB5 DGCR6 DMRT3 EED EIF4E2 ENKD1 ERBB2 EZH2 FAM83A GAS8 GEM GLYCTK GPATCH2L HEXIM2 HOXB5 HOXC8 HSPB7 ID3 IDH1 KANK2 LNX1 MIA3 MRPL32 MYPOP PALB2 PATZ1 PAX2 PLEKHF2 PPP1R32 PRKAB2 PRPF31 PSMA1 PTPRJ RAD51D RBM10 RCOR3 RUNX1T1 RUSC1 SCNM1 SNRPC SUZ12 TCAF1 TEAD4 TEKT4 TLE5 TRIM41 TSGA10 TTC32 TXK USP2 WDR25 ZNF250 ZNF587 ZNF835
Entrez ID		55668	63978
HPRD ID		16594	11457
Ensembl ID		ENSG00000089916	ENSG00000147596
Uniprot IDs		A0A024R6E4 A0A024R6J0 Q9NWQ4	Q9GZV8
PDB IDs
Enriched GO Terms of Interacting Partners?
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