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PRPF40A and NCKAP1L
Data Source:
BioGRID
(pull down)
PRPF40A
NCKAP1L
Description
pre-mRNA processing factor 40 homolog A
NCK associated protein 1 like
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
U1 SnRNP
Membrane
Nuclear Matrix
Nuclear Speck
U2-type Prespliceosome
Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Secretory Granule Membrane
SCAR Complex
Extracellular Exosome
Ficolin-1-rich Granule Membrane
Molecular Function
RNA Binding
Protein Binding
GTPase Activator Activity
Protein Binding
Protein Kinase Activator Activity
Protein-containing Complex Binding
Biological Process
MRNA Splicing, Via Spliceosome
Cytoskeleton Organization
Cell Cycle
Regulation Of Cell Shape
Cell Migration
Regulation Of Cytokinesis
MRNA Cis Splicing, Via Spliceosome
Cell Division
Cell Morphogenesis
B Cell Homeostasis
Myeloid Cell Homeostasis
Chemotaxis
Cell Migration
Maintenance Of Cell Polarity
Cell Projection Assembly
Neutrophil Chemotaxis
Positive Regulation Of Actin Filament Polymerization
Cortical Actin Cytoskeleton Organization
Positive Regulation Of B Cell Proliferation
Activation Of Protein Kinase Activity
Negative Regulation Of Interleukin-17 Production
Negative Regulation Of Interleukin-6 Production
Positive Regulation Of Cell Adhesion Mediated By Integrin
Erythrocyte Homeostasis
Negative Regulation Of Myosin-light-chain-phosphatase Activity
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Positive Regulation Of T Cell Proliferation
Positive Regulation Of Phosphorylation
Response To Drug
T Cell Homeostasis
Negative Regulation Of Apoptotic Process
Neutrophil Degranulation
Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of GTPase Activity
Positive Regulation Of B Cell Differentiation
Positive Regulation Of Gamma-delta T Cell Differentiation
Positive Regulation Of Lymphocyte Differentiation
Positive Regulation Of Erythrocyte Differentiation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neuron Projection Morphogenesis
Erythrocyte Development
B Cell Receptor Signaling Pathway
Positive Regulation Of Phagocytosis, Engulfment
Protein-containing Complex Assembly
Actin Polymerization-dependent Cell Motility
Positive Regulation Of Neutrophil Chemotaxis
Pathways
mRNA Splicing - Major Pathway
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Neutrophil degranulation
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Heel bone mineral density (
30598549
)
Memory dysfunction in frontotemporal lobe dementia (
29724592
)
Metabolite levels (
23823483
)
Pulse pressure (
30224653
)
Refractive error (
32231278
)
Hip circumference adjusted for BMI (
28552196
)
Obesity-related traits (
23251661
)
Interacting Genes
130 interacting genes:
ABI1
AKAP8L
APBB1IP
ARFGEF2
ASXL2
ATAD3A
BAG6
BEND7
BRD4
C4orf45
CAP2
CCNL1
CCT2
CCT4
CCT7
CDK12
CDK13
CHD3
CHERP
CPSF6
CT45A1
CUL1
CYFIP1
CYFIP2
DAAM1
DDIT4L
DHX15
DHX8
DHX9
DIAPH1
DZIP1
DZIP1L
ENAH
ERG
EVL
FASLG
FMN1
FMNL1
FMNL2
FMNL3
FN1
FNBP4
FRA10AC1
GAPDH
HIPK1
HNRNPF
HNRNPK
HNRNPU
HNRNPUL1
HSPB1
HSPG2
HTT
IL1RAP
KMT2B
LARP7
LTBP3
MAP1LC3A
MECP2
MMP11
NCKAP1L
NKAP
NKAPD1
NONO
PCBP2
PDCD7
PECAM1
PFKL
PIAS1
PIAS3
PIAS4
PICK1
PPIG
PRKAR1A
PSG5
PTPRF
RBM39
RBMX2
RCC2
RLF
RPL4
RPLP0
SDCBP
SDCBP2
SDK1
SERPINB9
SF1
SF3A1
SF3A2
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SMAD4
SNIP1
SNRNP70
SON
SREK1
SREK1IP1
SRPK2
STIM2
TCEAL9
U2AF1
U2AF2
U2SURP
UBE2I
UBE2K
UBQLN1
UBQLN2
UBQLN4
UBR4
VASP
VCL
WAS
WASF2
WASL
WBP11
WBP4
WIPF1
XRCC6
YBX1
YLPM1
YWHAG
ZCCHC10
ZCCHC8
ZFHX3
ZHX1
ZNF341
ZNF451
2 interacting genes:
GAS7
PRPF40A
Entrez ID
55660
3071
HPRD ID
10995
00781
Ensembl ID
ENSG00000196504
ENSG00000123338
Uniprot IDs
O75400
P55160
PDB IDs
1UZC
1YWI
1YWJ
1ZR7
2CQN
2DYF
2KZG
2L5F
2L9V
2LKS
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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