PIGV and ZNF593

Data Source:
BioGRID (biochemical)

		PIGV	ZNF593
Description		phosphatidylinositol glycan anchor biosynthesis class V	zinc finger protein 593
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Mannosyltransferase Complex	Nucleoplasm Nucleolus
	Molecular Function	Alpha-1,6-mannosyltransferase Activity Mannosyltransferase Activity Glycolipid Mannosyltransferase Activity Protein Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane Mannosylation	Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Blond vs. brown/black hair color ( 30531825) Blood protein levels in cardiovascular risk ( 28369058) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) LDL cholesterol ( 24097068 25961943) LDL cholesterol levels ( 28334899) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 27863252) Sum basophil neutrophil counts ( 27863252) Triglyceride levels ( 28334899 32154731) Triglycerides ( 24097068)
Interacting Genes			10 interacting genes: DDIT4L GPR3 LNX1 MAP3K20 MAP3K7 MAPK8IP2 PICK1 POLR1H RAB1A SRPK2
Entrez ID		55650	51042
HPRD ID		07912	15866
Ensembl ID		ENSG00000060642	ENSG00000142684
Uniprot IDs		Q9NUD9	O00488
PDB IDs			1ZR9 6LSS 6LU8
Enriched GO Terms of Interacting Partners?
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