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ASAP3 and ARF6
Data Source:
HPRD
(in vivo, in vitro)
ASAP3
ARF6
Description
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ADP ribosylation factor 6
Image
GO Annotations
Cellular Component
Ruffle
Nucleoplasm
Cytosol
Focal Adhesion
Intracellular Membrane-bounded Organelle
Ruffle
Cytoplasm
Endosome
Golgi Apparatus
Cytosol
Plasma Membrane
Focal Adhesion
Cell Cortex
Membrane
Endocytic Vesicle
Filopodium Membrane
Early Endosome Membrane
Cleavage Furrow
Recycling Endosome Membrane
Extracellular Exosome
Flemming Body
Presynapse
Glutamatergic Synapse
Molecular Function
GTPase Activator Activity
Protein Binding
Metal Ion Binding
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Thioesterase Binding
Protein N-terminus Binding
Biological Process
Cell Migration
Positive Regulation Of GTPase Activity
Regulation Of Stress Fiber Assembly
Liver Development
Intracellular Protein Transport
Cell Cycle
Cell Adhesion
Nervous System Development
Vesicle-mediated Transport
Cell Differentiation
Positive Regulation Of Actin Filament Polymerization
Cortical Actin Cytoskeleton Organization
Endocytic Recycling
Myeloid Cell Apoptotic Process
Protein Localization To Cell Surface
Regulation Of Rac Protein Signal Transduction
Protein Localization To Endosome
Negative Regulation Of Receptor-mediated Endocytosis
Synaptic Vesicle Endocytosis
Positive Regulation Of Protein Secretion
Cell Division
Regulation Of Filopodium Assembly
Positive Regulation Of Keratinocyte Migration
Regulation Of Dendritic Spine Development
Establishment Of Epithelial Cell Polarity
Ruffle Assembly
Hepatocyte Apoptotic Process
Maintenance Of Postsynaptic Density Structure
Positive Regulation Of Focal Adhesion Disassembly
Positive Regulation Of Protein Localization To Plasma Membrane
Regulation Of Presynapse Assembly
Cellular Response To Nerve Growth Factor Stimulus
Negative Regulation Of Protein Localization To Cell Surface
Negative Regulation Of Dendrite Development
Pathways
TBC/RABGAPs
Clathrin-mediated endocytosis
MET receptor recycling
Drugs
5'-Guanosine-Diphosphate-Monothiophosphate
Guanosine-5'-Diphosphate
Myristic acid
Diseases
GWAS
Cholesterol, total (
24097068
)
LDL cholesterol levels (
32203549
)
Total cholesterol levels (
28334899
)
Triglyceride levels (
32203549
)
Erythema nodosum in inflammatory bowel disease (
24487271
)
Interacting Genes
9 interacting genes:
ARF6
CRK
MTNR1A
PDZD3
REL
TCF4
TEPSIN
TFCP2
UBE3A
37 interacting genes:
AGAP1
AP1B1
AP3B1
AP3D1
AP3S2
APBB1
APP
ARFIP2
ARHGAP10
ARRB1
ARRB2
ASAP1
ASAP2
ASAP3
ATP6V0C
CAPN1
CHRM3
CYTH1
CYTH2
EXOC5
EZR
HTR2A
IKBKG
ITSN1
MEOX2
MT2A
PALS1
PIP5K1A
PIP5K1C
PLD1
RAB11A
RAB11FIP3
RAB11FIP4
RAB11FIP5
SMAP1
SPAG9
ZNF709
Entrez ID
55616
382
HPRD ID
11662
02714
Ensembl ID
ENSG00000088280
ENSG00000165527
Uniprot IDs
A0A024RAB1
B4DRP2
Q8TDY4
P62330
PDB IDs
2B0O
3LVQ
3LVR
1E0S
2A5D
2A5F
2A5G
2BAO
2BAU
2J5X
2W83
3LVQ
3LVR
3N5C
3PCR
4FME
4KAX
6BBP
6BBQ
6PAU
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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