TENT5A and EGLN2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TENT5A	EGLN2
Description		terminal nucleotidyltransferase 5A	egl-9 family hypoxia inducible factor 2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Protein Binding RNA Adenylyltransferase Activity	Protein Binding Ferrous Iron Binding 2-oxoglutarate-dependent Dioxygenase Activity Oxygen Sensor Activity L-ascorbic Acid Binding Peptidyl-proline Dioxygenase Activity Peptidyl-proline 4-dioxygenase Activity
	Biological Process	MRNA Stabilization	Regulation Of Cell Growth Response To Hypoxia Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Intracellular Estrogen Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Cell Redox Homeostasis Positive Regulation Of Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia
Pathways			Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Drugs			Ascorbic acid Roxadustat
Diseases
GWAS			Carotid intima media thickness (mean) ( 31801372) Chronic obstructive pulmonary disease ( 22080838) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Nicotine metabolite ratio in current smokers ( 28921760) Parental longevity (father's attained age) ( 29227965) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Red blood cell count ( 32888494) Smoking behavior ( 20418890) Smoking behaviour (cigarettes smoked per day) ( 30617275)
Interacting Genes		32 interacting genes: ARID5A ATXN1 BAG6 BCCIP BHLHE40 CD93 COL4A2 DMRTB1 DYNC1H1 EGLN2 GLIS2 HDLBP HTRA1 HYPK KEAP1 KRTAP26-1 NR2F2 PSG3 RHOXF2 RIN3 RNF14 RNF44 ROR2 SNRPC SPINT1 TBX4 TENT5B TNS2 TOLLIP YPEL3 ZC3H10 ZFYVE9	11 interacting genes: A2M CDK2 EPAS1 HIF1A HIF3A MFHAS1 MOB4 PRKCA SPOP SRPK2 TENT5A
Entrez ID		55603	112398
HPRD ID		13311	06970
Ensembl ID		ENSG00000112773	ENSG00000269858
Uniprot IDs		Q96IP4	A0A024R0R2 Q96KS0
PDB IDs			5V1B
Enriched GO Terms of Interacting Partners?
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