UBE2Q1 and RNF7

Data Source:
BioGRID (two hybrid)

		UBE2Q1	RNF7
Description		ubiquitin conjugating enzyme E2 Q1	ring finger protein 7
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GO Annotations	Cellular Component	Nucleus Cytosol Filopodium	Nucleus Nucleoplasm Cytoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Cullin Family Protein Binding
	Biological Process	Protein Polyubiquitination Suckling Behavior Embryo Implantation Mating Behavior Fertilization Reproductive System Development Prolactin Secretion	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Phosphopantetheinylation Post-translational Protein Modification Protein Neddylation Response To Redox State
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)	Hepatitis C induced liver fibrosis ( 22841784) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		12 interacting genes: ECPAS FHL3 IRF2BPL ITCH LMNA MDM2 RNF26 RNF31 RNF7 STUB1 TP53 UBC	43 interacting genes: APOBEC3F APOBEC3G ASB11 BTRC CASP7 CBFB CDC34 CHFR CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS ELOB ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBE2C UBE2D1 UBE2D2 UBE2D4 UBE2F UBE2L3 UBE2M UBE2Q1 UBE2S
Entrez ID		55585	9616
HPRD ID		15601	04840
Ensembl ID		ENSG00000160714	ENSG00000114125
Uniprot IDs		Q7Z7E8	Q9UBF6
PDB IDs		2QGX	2ECL
Enriched GO Terms of Interacting Partners?
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