GPRC5D and TWSG1

Data Source:
BioGRID (two hybrid)

		GPRC5D	TWSG1
Description		G protein-coupled receptor class C group 5 member D	twisted gastrulation BMP signaling modulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome	Extracellular Space
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity	Protein Binding Transforming Growth Factor Beta Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase Activity	Ossification Mesoderm Formation Negative Regulation Of Cytokine Production Transforming Growth Factor Beta Receptor Signaling Pathway Salivary Gland Morphogenesis Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Hemopoiesis Cell Differentiation BMP Signaling Pathway Regulation Of BMP Signaling Pathway Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Forebrain Development Camera-type Eye Development Negative Regulation Of Osteoblast Differentiation Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Pathways
Drugs
Diseases
GWAS			Dental caries ( 23064961)
Interacting Genes		30 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1	10 interacting genes: BMP1 BMP4 CHRD FAM209A FNDC9 GJA8 GPRC5D LRRC4C SGTA TNS2
Entrez ID		55507	57045
HPRD ID		07604	05443
Ensembl ID		ENSG00000111291	ENSG00000128791
Uniprot IDs		Q9NZD1	Q9GZX9
PDB IDs
Enriched GO Terms of Interacting Partners?
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