SYNJ2BP and TMEM101

Data Source:
BioGRID (two hybrid)

		SYNJ2BP	TMEM101
Description		synaptojanin 2 binding protein	transmembrane protein 101
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Ionotropic Glutamate Receptor Complex Basolateral Plasma Membrane Cell Junction Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane	Cellular_component Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		33 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1	21 interacting genes: BNIP3 C4orf3 CCR4 DRD2 GIMAP1 GPR182 MAP4K1 NDUFA3 NINJ2 NPSR1 PDZK1IP1 PKMYT1 STRIT1 STX10 SYNJ2BP TMEM243 TMEM65 TMIE VAMP1 VAMP2 VAPB
Entrez ID		55333	84336
HPRD ID		15455	14623
Ensembl ID		ENSG00000213463	ENSG00000091947
Uniprot IDs		A0A024R670 P57105	B4DFS4 Q96IK0
PDB IDs		2ENO 2JIK 2JIN
Enriched GO Terms of Interacting Partners?
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