RPRD1A and RIOK2

Data Source:
BioGRID (two hybrid)

		RPRD1A	RIOK2
Description		regulation of nuclear pre-mRNA domain containing 1A	RIO kinase 2
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GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase II, Holoenzyme	Nucleus Nucleoplasm Cytoplasm Cytosol Preribosome, Small Subunit Precursor
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding	Protein Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	MRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II Dephosphorylation Of RNA Polymerase II C-terminal Domain	Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis Protein Autophosphorylation Positive Regulation Of Ribosomal Small Subunit Export From Nucleus Positive Regulation Of RRNA Processing
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs			Fostamatinib
Diseases
GWAS		Drug-induced torsades de pointes ( 24223155) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)	Chronic mountain sickness ( 31417607) Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: BCAR3 FAM90A1 HGS KDM1A KPNA3 LONRF1 NXF1 RIOK2 RPRD1B SDCBP YWHAZ ZNF410 ZNF76	7 interacting genes: APP CSNK2A1 GFUS PRDM16 RELA RPRD1A SMAD3
Entrez ID		55197	55781
HPRD ID		10134	10193
Ensembl ID		ENSG00000141425	ENSG00000058729
Uniprot IDs		A0A024RC37 A0A0C4DGQ6 Q96P16	Q9BVS4
PDB IDs		4JXT 4NAC	5DHF 6FDM 6FDN 6FDO 6G18 6G51 6HK6
Enriched GO Terms of Interacting Partners?
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