CCDC198 and IQGAP3

		CCDC198	IQGAP3
Description		coiled-coil domain containing 198	IQ motif containing GTPase activating protein 3
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Cell-cell Junction Lateral Plasma Membrane
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Calmodulin Binding Actin Filament Binding Myosin VI Light Chain Binding
	Biological Process		G1/S Transition Of Mitotic Cell Cycle Activation Of MAPK Activity Ras Protein Signal Transduction Regulation Of Cell Size Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Positive Regulation Of GTPase Activity ERK1 And ERK2 Cascade Cellular Response To Organic Substance
Pathways			RHO GTPases activate IQGAPs
Drugs
Diseases
GWAS			Adult body size ( 32376654) Creatine kinase levels ( 29403010)
Interacting Genes		27 interacting genes: CBY2 FAM9B FHL2 FHL3 FKBP6 GOLGA2 GOPC HOOK2 HSF2BP IQGAP3 KIFC3 KRT31 KRT34 KRT40 LZTS2 MDFI MTUS2 PDE4DIP PFDN5 PNMA1 SIAH1 SMAD3 SSX2IP TEX11 TRAF1 TRAF2 TRIM27	2 interacting genes: CALM2 CCDC198
Entrez ID		55195	128239
HPRD ID		12628	11051
Ensembl ID		ENSG00000100557	ENSG00000183856
Uniprot IDs		B7ZL43 E9PSE9 F5GWJ3 Q05C89 Q9NVL8	Q86VI3
PDB IDs			3ISU
Enriched GO Terms of Interacting Partners?
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