CC2D1A and CHMP4C

Data Source:
HPRD (two hybrid)

		CC2D1A	CHMP4C
Description		coiled-coil and C2 domain containing 1A	charged multivesicular body protein 4C
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Microtubule Organizing Center Cytosol Plasma Membrane Membrane Extracellular Exosome	ESCRT III Complex Multivesicular Body Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Late Endosome Membrane Flemming Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Cadherin Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of SnRNA Transcription By RNA Polymerase II	Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Negative Regulation Of Cytokinesis Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Mitotic Cytokinesis Checkpoint Regulation Of Viral Process Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell
Pathways			Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases		Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
GWAS			Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)
Interacting Genes		4 interacting genes: CDC37 CHMP4A CHMP4C LRP1	10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A
Entrez ID		54862	92421
HPRD ID		08616	18135
Ensembl ID		ENSG00000132024	ENSG00000164695
Uniprot IDs		Q6P1N0	Q96CF2
PDB IDs			3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?
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