BCAS3 and PELP1

Data Source:
BioGRID (pull down, pull down)

		BCAS3	PELP1
Description		BCAS3 microtubule associated cell migration factor	proline, glutamate and leucine rich protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoplasmic Microtubule Cell Leading Edge Transcriptionally Active Chromatin Intermediate Filament Cytoskeleton	Nucleoplasm Nucleolus Cytoplasm Transcriptionally Active Chromatin MLL1 Complex
	Molecular Function	Chromatin Binding Protein Binding Transcription Factor Binding Acetyltransferase Activator Activity Histone Acetyltransferase Binding Nuclear Hormone Receptor Binding Histone Binding Beta-tubulin Binding	Chromatin Binding RNA Binding Protein Binding Transcription Factor Binding
	Biological Process	Angiogenesis Golgi Organization Positive Regulation Of Endothelial Cell Migration Microtubule Organizing Center Organization Negative Regulation Of GTPase Activity Tube Formation Response To Starvation Positive Regulation Of Catalytic Activity Positive Regulation Of GTPase Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Filopodium Assembly Negative Regulation Of Focal Adhesion Assembly Cellular Response To Estrogen Stimulus Positive Regulation Of Intracellular Protein Transport Activation Of GTPase Activity Regulation Of Establishment Of Cell Polarity Positive Regulation Of Actin Cytoskeleton Reorganization	RRNA Processing Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Estrogen Stimulus
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol PTK6 Expression
Drugs
Diseases
GWAS		Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Alzheimer's disease (cognitive decline) ( 23535033) Blood urea nitrogen levels ( 31152163 29403010) Bone ultrasound measurement (broadband ultrasound attenuation) ( 28472463) Calcium levels ( 29403010) Chronic kidney disease ( 31152163 20383146) Coronary artery disease ( 32469254 29212778 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31451708 29779033 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) FEV1 ( 30804560) Glomerular filtration rate ( 27588450 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Gout ( 32238385 25967671) Gout (combined type) ( 32238385) Heel bone mineral density ( 30598549 28869591) Height ( 18391951) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Immune reponse to smallpox (secreted IL-2) ( 22610502) Intraocular pressure ( 29617998 29785010 31959993 30054594) Lung function (FEV1/FVC) ( 30804560) Macular thickness ( 30535121) Medial orbital frontal cortex volume ( 31530798) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Metabolite levels (small molecules and protein measures) ( 27005778) Myocardial infarction ( 26343387) Obesity-related traits ( 23251661) Optic cup area ( 25631615 31798171 28073927) Optic disc size ( 31809533) Platelet count ( 32888494) Plateletcrit ( 32888494) Pulse pressure ( 30578418) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494) Refractive error ( 32231278) Renal function-related traits (BUN) ( 22797727) Renal function-related traits (eGRFcrea) ( 22797727) Renal function-related traits (sCR) ( 22797727) Serum creatinine levels ( 29779033) Serum uric acid levels ( 30993211 29403010 32514006) Systolic blood pressure ( 30224653 30578418) Thyroid stimulating hormone levels ( 30367059 32769997) Urate levels ( 31985003 31578528 23263486) Urolithiasis ( 30975718) Vertical cup-disc ratio ( 20548946) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Eosinophil counts ( 29403010)
Interacting Genes		21 interacting genes: ATM BAG4 CCND1 CDC23 CTBP1 CTBP2 FBXW7 H3C1 KRAS MTDH PALB2 PELP1 PHB PLEKHF2 PTPN1 SMAD4 STK11 TGFB1 TSG101 XRCC3 ZDHHC17	25 interacting genes: AR BAG6 BCAS3 BLOC1S1 CREBBP EP300 ESR1 ESR2 H1-1 H2AC20 H2BC21 H3-3A H4C1 HGS NFKB1 NR3C1 PTEN RB1 SMAD9 SNCA SRC STAT3 SUMO2 TOM1L1 TP53
Entrez ID		54828	27043
HPRD ID		06313	10144
Ensembl ID		ENSG00000141376	ENSG00000141456
Uniprot IDs		K7ESE9 Q05D99 Q9H6U6	B4DEX7 B4DR36 C9JFV4 E7EV54 Q8IZL8
PDB IDs
Enriched GO Terms of Interacting Partners?
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