PPIC and CAPNS2

		PPIC	CAPNS2
Description		peptidylprolyl isomerase C	calpain small subunit 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Intracellular Membrane-bounded Organelle Extracellular Exosome	Cytosol Plasma Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Folding	Proteolysis Extracellular Matrix Disassembly
Pathways			Degradation of the extracellular matrix Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs		Proline
Diseases
GWAS		Aortic root size ( 19584346) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Diverticular disease ( 30177863) Subcortical volume (MOSTest) ( 32665545)	Thyroid hormone levels ( 23408906)
Interacting Genes		13 interacting genes: ARSA BANP CAPNS2 FAM25A FAM25C FAM25G LGALS3BP SGTA SGTB UBAP1 UBQLN1 UBQLN2 UBQLN4	9 interacting genes: APP ARMC10 CAPN2 CMTM5 OXNAD1 PHACTR3 PPIC PRPF31 RIN1
Entrez ID		5480	84290
HPRD ID		00459	16682
Ensembl ID		ENSG00000168938	ENSG00000256812
Uniprot IDs		P45877	Q96L46
PDB IDs		2ESL
Enriched GO Terms of Interacting Partners?
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