ARL15 and PDE6D

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		ARL15	PDE6D
Description		ADP ribosylation factor like GTPase 15	phosphodiesterase 6D
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Cilium Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Molecular_function Protein Binding GTP Binding	GTPase Inhibitor Activity Protein Binding Small GTPase Binding
	Biological Process	Biological_process	Visual Perception Negative Regulation Of GTPase Activity Response To Stimulus
Pathways			ARL13B-mediated ciliary trafficking of INPP5E RAS processing
Drugs
Diseases
GWAS		Adiponectin levels ( 20011104 22479202 31178129) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Alcohol dependence (age at onset) ( 24962325) Alcoholic chronic pancreatitis ( 28754779) Apolipoprotein A1 levels ( 32203549) Brown vs. black hair color ( 30531825) Circulating leptin levels or type 2 diabetes ( 32341051) Coffee consumption ( 31046077) Coronary artery disease ( 29212778) Emphysema imaging phenotypes ( 26030696) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) FEV1 ( 30804560) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glycine levels ( 30837465) HDL cholesterol ( 24097068 30275531 20686565) HDL cholesterol levels ( 32203549 28334899) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Lung function (FVC) ( 28166213 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolite levels ( 31628463) Monobrow ( 27182965) Night sleep phenotypes ( 27126917) Pulse pressure ( 27841878) Refractive error ( 32231278) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Rheumatoid arthritis ( 23918589) Right lateral prefrontal cortical growth ( 29682794) Systolic blood pressure ( 27841878) Systolic blood pressure (dietary potassium intake interaction) ( 29212900) Triglyceride levels ( 32203549 32154731) Triglycerides ( 30275531) Type 2 diabetes ( 24509480 30054458 29358691 30297969 30718926 28869590) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532) Urinary magnesium excretion ( 31993563) Urinary magnesium-to-creatinine ratio ( 29093028) Waist circumference adjusted for body mass index ( 25673412) Youthful appearance (self-reported) ( 32339537)	Eating disorders (purging via substances) ( 23568457) Height ( 18391951)
Interacting Genes		14 interacting genes: B4GALT3 CCDC90B CRMP1 FUNDC2 GAPDH GRIPAP1 MEOX2 PDE6D PTN RPL8 TFG TUBB2A UBR1 UNC119	25 interacting genes: ARL15 ARL16 ARL2 ARL3 CDC42 CETN3 FAM219A GNAI1 GRK1 GRK7 HRAS OTP PTGIR RAB13 RAB18 RAB8A RAD23A RAP1A RAP2B RASA1 RHEB RHOA RHOB RND1 RPGR
Entrez ID		54622	5147
HPRD ID		12471	04056
Ensembl ID		ENSG00000185305	ENSG00000156973
Uniprot IDs		Q9NXU5	B8ZZK5 O43924 Q6IB24
PDB IDs			1KSG 1KSH 1KSJ 3T5G 3T5I 4JHP 4JV6 4JV8 4JVB 4JVF 5E80 5E8F 5F2U 5ML2 5ML3 5ML4 5ML6 5ML8 5NAL 5TAR 5TB5 5X72 5X73 5X74 5YAV 5YAW
Enriched GO Terms of Interacting Partners?
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