POU2F1 and SOX2

  • Data Source:
  • BioGRID (proximity labelling technology)
  • HPRD (in vitro)

POU2F1

SOX2

Description POU class 2 homeobox 1 SRY-box transcription factor 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 31959851 31619474)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444)
  • Diastolic blood pressure ( 30224653)
  • Liver enzyme levels ( 18940312)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes 68 interacting genes: APP AR ARPC3 ARRB1 BARD1 BRCA1 CEBPE CREB1 CREM ESR1 FDXR HCFC1 HIVEP1 HMGA1 HMGB2 HNF1A HOXB13 HOXC9 IRF9 LIFR MLLT10 MNAT1 MSX1 NCOR2 NFYA NPAT NR3C1 PARP1 PBX1 PGR PKNOX1 PLK3 POGZ POU2AF1 POU6F2 PPIP5K2 PRKACA PRKDC PRR20A PRR20B PRR20C PRR20D PRR20E RARA RELA RXRA SNAPC4 SNIP1 SNX24 SOX2 SP1 SP4 STAT5A STAT5B STOX1 TBP THRA TLE4 TLE5 TLX2 TNF TXNRD1 UBE2I VDR XRCC6 ZC3H10 ZFHX3 ZMYM6 17 interacting genes: AKT1 ALX4 CASP8 CDX1 COP1 FZR1 L3MBTL3 MAPK3 NR5A1 OTUD7B POU2F1 POU5F1 SETD7 SUMO1 UBE2D3 UBR5 XPO1
Entrez ID 5451 6657
HPRD ID 01250 08921
Ensembl ID ENSG00000143190 ENSG00000181449
Uniprot IDs A0A024R8Y2 P14859 A0A0U3FYV6 P48431
PDB IDs 1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU 1O4X 2LE4 6T7B 6T90 6WX7 6WX8 6WX9 6YOV
Enriched GO Terms of Interacting Partners?
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