PLEKHA5 and EXTL3

Data Source:
BioGRID (two hybrid)

		PLEKHA5	EXTL3
Description		pleckstrin homology domain containing A5	exostosin like glycosyltransferase 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Postsynaptic Density Membrane Glutamatergic Synapse	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase Activity Protein Binding Transferase Activity, Transferring Glycosyl Groups Metal Ion Binding
	Biological Process	Biological_process Reproductive System Development	Protein Glycosylation Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Cell Growth IRE1-mediated Unfolded Protein Response
Pathways		Synthesis of PIPs at the plasma membrane	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Adult body size ( 32376654) Chronic mountain sickness ( 31417607) Daytime sleep phenotypes ( 27126917) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Pharmacokinetics of antiepileptic drugs in severe mental disorder (concentration drug ratio) ( 25944848) Platelet reactivity in response to clopidogrel treatment ( 32472697) Thalamus volume ( 31530798)	Height ( 25429064) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Moderate-to-late spontaneous preterm birth ( 31194736)
Interacting Genes		31 interacting genes: ARHGEF9 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 SH3BP5L SOGA1 SPTAN1 SPTBN1 SRPK2 UPF1 WASH2P YWHAG	2 interacting genes: ATXN1 PLEKHA5
Entrez ID		54477	2137
HPRD ID		09684	09306
Ensembl ID		ENSG00000052126	ENSG00000012232
Uniprot IDs		A0A024RAY7 Q9HAU0	A0A384NPY9 O43909
PDB IDs		2DKP
Enriched GO Terms of Interacting Partners?
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