FXYD6 and HAUS2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FXYD6	HAUS2
Description		FXYD domain containing ion transport regulator 6	HAUS augmin like complex subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Centrosome Cytosol HAUS Complex Mitotic Spindle Microtubule
	Molecular Function	Molecular_function Protein Binding Sodium Channel Regulator Activity Ion Channel Regulator Activity	Molecular_function Protein Binding
	Biological Process	Biological_process Ion Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity	G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking
Pathways		Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321) Myopia ( 27182965)	Bipolar disorder ( 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		65 interacting genes: APCDD1L APH1A AQP6 ARL13B BCAR1 C4BPA CCDC90B CD74 CERS4 CLDN7 CLEC10A CREB3 CREB3L1 DERL2 EBP ELOVL2 ELOVL4 ERGIC3 FCER1G FFAR2 FPR2 GDF9 GJA8 GPR42 HAUS2 JAGN1 KCNJ6 LHFPL2 LHFPL5 LMNA MFF MGST3 MMGT1 OCIAD1 PEX12 PGRMC2 PPP1CC RBM48 RHBDL1 RHCG RNASEK SLC10A1 SLC10A6 SLC16A7 SLC30A2 SLC35C2 SLC35E1 SLC35E3 SLC39A2 SLC47A1 SVOP TLCD4 TLE1 TM4SF18 TMEM154 TMEM237 TMEM239 TMEM31 TMEM35A TMEM72 TMEM86B TMPPE TP53 TRIM27 UNC119	3 interacting genes: FXYD6 MAPK6 XRCC4
Entrez ID		53826	55142
HPRD ID		09456	07675
Ensembl ID		ENSG00000137726	ENSG00000137814
Uniprot IDs		A0A024R3J8 Q9H0Q3	A0A024R9M5 A0A024R9P0 H3BP16 Q9NVX0
PDB IDs
Enriched GO Terms of Interacting Partners?
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