PLRG1 and CNN1

		PLRG1	CNN1
Description		pleiotropic regulator 1	calponin 1
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GO Annotations	Cellular Component	Prp19 Complex Fibrillar Center Nucleus Nucleoplasm DNA Replication Factor A Complex Nuclear Speck Nuclear Membrane U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Cul4-RING E3 Ubiquitin Ligase Complex	Cytoskeleton Focal Adhesion
	Molecular Function	Protein Binding	Actin Binding Protein Binding Calmodulin Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Localization To Nucleus Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Smooth Muscle Contraction Actomyosin Structure Organization Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Fibrinogen ( 21757653) Fibrinogen levels ( 29403010 28107422)	Presence of antiphospholipid antibodies ( 27098658)
Interacting Genes		14 interacting genes: APP CDC5L CNN1 HNRNPM MIR106B MIR205 MIR93 MIRLET7A2 MIRLET7E MIRLET7G MIRLET7I MX1 SF3B1 ZSCAN1	15 interacting genes: ACTA1 ADRB2 CALM1 CCHCR1 COG6 DNMBP FYN MYO1A NCAPD2 PLRG1 PRKCE SYCE1 TFPT TPM3 TUBB
Entrez ID		5356	1264
HPRD ID		16181	02884
Ensembl ID		ENSG00000171566	ENSG00000130176
Uniprot IDs		O43660	B7Z7E1 P51911 Q53FP8 V9HWA5
PDB IDs		4YVD 5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM	1WYP
Enriched GO Terms of Interacting Partners?
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