PITX2 and UFSP1

  • Data Source:
  • BioGRID (two hybrid)

PITX2

UFSP1

Description paired like homeodomain 2 UFM1 specific peptidase 1 (inactive)
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Heart rate increase in response to exercise ( 29497042)
  • Heart rate response to recovery post exercise (20 sec) ( 29497042)
  • Heart rate response to recovery post exercise (30 sec) ( 29497042)
  • Heart rate response to recovery post exercise (40 sec) ( 29497042)
  • Heart rate response to recovery post exercise (50 sec) ( 29497042)
  • Nonunion in individuals with fractures ( 30680360)
  • Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
  • Resting heart rate ( 29769521 27798624 20639392)
Interacting Genes 36 interacting genes: ATN1 CTNNB1 CYSRT1 DAZAP2 DYNLT1 HDAC1 HERC5 HEY1 HOXA1 KAT5 KRT34 KRTAP15-1 KRTAP19-5 KRTAP19-7 KRTAP3-3 KRTAP6-1 KRTAP7-1 LEF1 OIP5 PDLIM1 PFDN5 POU2AF1 PROP1 PSMB4 RBPMS TEX37 TINAGL1 TLE5 TRAF1 TRIB3 TRIM25 UFSP1 VGLL3 WWOX ZNF34 ZNHIT3 42 interacting genes: C10orf55 CIDEB CIDEC COG6 CREB5 CSTF2 FAM222B FANCL FOXH1 FOXI1 GLYCTK GPSM3 HNF1B HOXC9 HSF4 INCA1 KRTAP15-1 LASP1 MSRB3 MYOZ3 PITX1 PITX2 POGZ POU6F2 PROP1 PRR22 RAPGEF3 RBPMS2 RUSC1 SMARCC1 SNRPC SPG21 TBX3 TCF7L2 TLX3 UBQLN2 VAC14 VAX2 VGLL3 VPS37C WWOX ZIC1
Entrez ID 5308 402682
HPRD ID 03328 18630
Ensembl ID ENSG00000164093 ENSG00000176125
Uniprot IDs Q99697 Q6NVU6
PDB IDs 2L7F 2L7M 2LKX
Enriched GO Terms of Interacting Partners?
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