PIN1 and GOLGA2

Data Source:
BioGRID (two hybrid)

		PIN1	GOLGA2
Description		peptidylprolyl cis/trans isomerase, NIMA-interacting 1	golgin A2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Nuclear Speck Midbody Ciliary Basal Body Neuron Projection Glutamatergic Synapse Postsynaptic Cytosol	Golgi Cis Cisterna Golgi Membrane Spindle Pole Golgi Apparatus Cis-Golgi Network Microtubule COPII-coated ER To Golgi Transport Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitotic Spindle
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Motor Activity Protein Binding Beta-catenin Binding Cis-trans Isomerase Activity Mitogen-activated Protein Kinase Kinase Binding GTPase Activating Protein Binding Tau Protein Binding Phosphoserine Residue Binding Phosphothreonine Residue Binding Phosphoprotein Binding	Protein Binding Microtubule Binding Protein Kinase Binding Syntaxin Binding Identical Protein Binding Cadherin Binding Importin-alpha Family Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Response To Hypoxia Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Cell Cycle Regulation Of Mitotic Nuclear Division Regulation Of Gene Expression Neuron Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Stability Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Regulation Of Cytokinesis Negative Regulation Of Type I Interferon Production Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Catabolic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of GTPase Activity Positive Regulation Of Transcription By RNA Polymerase II Microtubule Polymerization Synapse Organization Protein Stabilization Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Cell Motility	Protein Glycosylation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Microtubule Nucleation Golgi Organization Centrosome Cycle Asymmetric Cell Division Negative Regulation Of Autophagy Protein Transport Negative Regulation Of Protein Binding COPII Vesicle Coating Spindle Assembly Protein Homotetramerization Positive Regulation Of Protein Glycosylation Golgi Ribbon Formation Golgi Disassembly Spindle Assembly Involved In Meiosis Mitotic Spindle Assembly Positive Regulation Of Ubiquitin Protein Ligase Activity
Pathways		ISG15 antiviral mechanism RHO GTPases Activate NADPH Oxidases Regulation of TP53 Activity through Phosphorylation PI5P Regulates TP53 Acetylation Negative regulators of DDX58/IFIH1 signaling	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs		Beta-(2-Naphthyl)-Alanine 3,6,9,12,15,18-HEXAOXAICOSANE
Diseases
GWAS		Sleep duration ( 25469926)	Adult body size ( 32376654) Body mass index ( 26426971)
Interacting Genes		263 interacting genes: ABI2 ADAMTSL4 ADARB1 AJUBA AMOT ANKRD40 AP2A1 APLP1 APP ARHGEF15 ARID5A ATCAY ATN1 ATP5F1B BAG6 BARD1 BCL11A BCL2 BCL6 BCLAF1 BRCA1 BRD8 C3orf36 CAPRIN1 CARHSP1 CASP6 CBFA2T3 CBS CBY2 CCDC153 CCDC184 CCDC33 CCDC6 CCDC88B CCDC90B CCNB1 CCNE1 CCNK CDC25C CDC27 CDK1 CDK11A CDK11B CDK12 CDK2 CDK9 CDKN1B CENPB CEP55 CEP76 CHAMP1 CHPF CNKSR1 COL11A2 CPEB1 CPNE6 CSAD CSNK2A1 CSNK2A2 CSNK2B CTNNB1 DAB1 DAB2 DDAH2 DDB1 DDX17 DDX24 DDX3X DDX5 DEAF1 DHX15 DMPK DYNC1I1 E2F4 EFS EFTUD2 EIF3G EP300 ETV6 EYA2 FAAP20 FADD FASLG FHL5 FOS FOSL1 FOXI1 FOXN1 FOXO4 FOXP2 FRS2 FUCA2 G3BP1 G3BP2 GGA2 GLI1 GMEB2 GOLGA2 GOLGA6L9 GPAA1 GPHN GPR152 HADHA HEXIM2 HNRNPC HNRNPH1 HNRNPK HNRNPU HOMEZ HOXA1 IKZF1 IKZF3 INO80E JAKMIP2 JUN KCTD7 KIF20B KIF5A KIFC3 KLHL20 KMT2B KRT31 KRT34 KRT37 KRT38 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 LCN2 LEPR LRIF1 MAP1S MAP3K11 MAPT MCL1 MDFI MED1 MEOX1 MEOX2 MLLT6 MOCS1 MTFR1 MTUS2 MYF5 MYT1 NAB2 NCKIPSD NCOA3 NCOR2 NEK6 NELFA NEUROD4 NFATC2 NONO NR4A3 NUP35 NUP62 PABPC1 PAX6 PBX1 PDLIM7 PKIB PKM PKMYT1 PLAGL2 PLEKHG2 PLK1 PML PNMA1 POLR2A PRPF8 PRRC1 PTOV1 PTPN1 QARS1 RAB4A RAF1 RAI1 RARA RBBP8 RBBP8NL RBPMS RELA REPS1 RNF208 RNPS1 RPL4 RPS6KB1 SCAI SCYL1 SELENOV SFPQ SGK1 SHKBP1 SMAD3 SNCAIP SNRNP200 SOCS3 SREK1 SRRM1 SRRM2 SRSF11 SSBP2 SSBP3 SSBP4 SSC5D STIL SUPT5H TAB3 TBC1D4 TCF12 TCF4 TFG TFPT THAP7 THRAP3 TLE3 TNIP1 TNS2 TOP2A TOX3 TP53 TP63 TP73 TRAF1 TRAF2 TRIM27 TRIM59 TRIP6 TRMT2A TSC2 TSC22D4 TUT1 U2AF2 UBB UBQLN2 UBQLN4 UBXN2B UNC119 VIRMA WEE1 WIZ WRNIP1 XRCC6 ZBTB14 ZBTB2 ZBTB22 ZBTB42 ZBTB7B ZBTB9 ZCCHC10 ZMIZ2 ZNF446 ZNF449 ZNF526 ZNF768 ZNF783	461 interacting genes: ABHD17A ABLIM1 ADAP1 AFF4 ALKBH2 ALKBH3 AMOTL2 ANKHD1 ANKRD11 ANKRD36 ANKRD36BP1 ANKS1A APC AQP1 ARFIP2 ARHGAP45 ARHGEF6 ARID5A ARL16 ARL4A ARNT2 ARPC3 ATP5PO ATP6V1C2 ATP6V1D ATP6V1G1 ATXN7 AXIN1 BAHD1 BARD1 BAZ2B BCAS2 BCL6 BCL6B BMS1P1 BYSL C12orf50 C19orf44 C1orf109 C1orf35 C2CD6 CAB39 CAPN7 CBX8 CBY2 CCAR1 CCDC120 CCDC13 CCDC146 CCDC150 CCDC17 CCDC185 CCDC187 CCDC198 CCDC70 CCDC87 CCDC92 CCHCR1 CCNC CCNH CDC20B CDC37 CDC5L CDC7 CDC73 CDCA7L CDK1 CDK18 CDKL3 CDKN1A CENPP CEP55 CEP57L1 CEP95 CHCHD2 CHCHD3 CIC CINP CKB CLIP3 COG6 CORO1A COX5B CRACR2A CRMP1 CSPP1 CSTF2T CUL5 CWF19L2 CYB5R2 DAXX DCTN4 DCX DDX6 DEUP1 DGCR6 DLGAP3 DLGAP5 DLX6-AS1 DMTN DNM2 DTX2 DVL2 EAF2 EFCAB6 EFHC1 EGR2 EIF3G EIF4A2 ENKD1 ENPP7 EP300 ERCC3 ESCO2 EXOC8 EXOSC5 FAM110A FAM124B FAM126B FAM161A FAM161B FAM184A FAM193B FAM207A FAM214A FAM214B FAM50B FAM90A1 FANCG FBF1 FBXL18 FBXO28 FIP1L1 FNDC11 FOXC2 GADD45GIP1 GAS2L2 GAS8 GATA1 GATA2 GATAD2B GCC1 GEM GFAP GGA2 GGN GLYCTK GMCL1 GNG5 GNL3L GORASP1 GORASP2 GPANK1 GPKOW GPS2 GRAP2 GRB14 GSE1 GTPBP10 GZMA GZMK HAUS1 HDAC4 HGS HOXB5 HOXB9 HTRA1 HYLS1 IFT20 IFT27 IGFN1 IHO1 IKZF3 IL16 INPP5J IQCE IQUB ISCU ITGB5 ITPKB ITSN2 KANK2 KANSL1 KAT5 KDM1A KIAA1217 KIFC3 KRT1 KRT18 KRT6A KRT6B KRT6C KRT75 L3MBTL2 LASP1 LATS1 LCOR LCP2 LENG1 LGALS3 LHX4 LIMS2 LIN7A LINGO1 LMNB2 LMO1 LMO2 LMO3 LMO4 LYPLA1 LYSMD1 MAB21L2 MAGOH MAGOHB MBD3 MCM10 MCM7 MCRS1 MFAP1 MID2 MISP MNAT1 MORF4L1 MORF4L2 MORN3 MOS MSRB3 MTFR2 MVP MYEF2 NCF2 NDC80 NDE1 NDEL1 NDN NDUFA5 NEBL NECAB2 NEFL NME7 NOS3 NOTCH1 NSMF NTAQ1 NUDT21 NXT2 OAS1 ODAD4 ORC1 PACRGL PARD6B PATL1 PCM1 PIAS2 PIBF1 PID1 PIK3R2 PIMREG PIN1 PITX1 PKN1 PKN3 PKP1 PKP2 PKP4 PLAAT5 PLEKHA2 POLDIP3 POLR3C POM121 POU4F3 PPP1R16B PPP1R18 PPP1R32 PPP2CA PQBP1 PRAM1 PRKAA1 PRKAA2 PRKAB2 PRPF18 PRPF3 PRPF31 PSMA1 PSMA4 PTBP2 PTPN11 PTPN21 RAB1A RAB1B RAB2A RAB2B RAB33B RAB39A RAB39B RAB6A RAD18 RAMAC RANBP3 RANBP3L RBL1 RBM17 RBM22 RBM25 RBM39 RBM41 RCL1 RCOR3 RGS8 RHNO1 RHOJ RHPN1 RIBC1 RIN1 RITA1 RNF135 RNF169 RNF213 RNF214 RNF6 RSPH14 RSRC2 RTP5 RUSC2 RXRB SAMD4A SAP30BP SCAF8 SCEL SCNM1 SECISBP2 SELENOV SFI1 SH2D4A SH3GLB2 SH3RF2 SHC3 SHISA6 SLU7 SMARCB1 SMARCE1 SMCP SMG9 SNAP47 SNF8 SNRPB SNRPB2 SNRPC SNTA1 SNW1 SNX18 SORBS2 SPATA18 SPATA2 SPATA22 SPG21 SRSF2 SSX2IP STAC STAMBPL1 STK25 STK26 STN1 SUDS3 SUGP2 SUPT5H SYNPO2L SYT17 SYT6 TBC1D22B TBC1D30 TBP TCEA2 TCEANC TCF19 TCL1A TDP2 TEAD4 TEPSIN TEX9 TFAP4 TFIP11 THAP7 THYN1 TLE5 TMED2 TPM1 TPRX1 TPX2 TRAF1 TRAF3IP2 TRAF4 TRAF5 TRIM14 TRIM29 TRIM42 TSC22D4 TSGA10 TSGA10IP TSHZ2 TSHZ3 TSSC4 TSSK3 TTC23 TTC9C TTPA TUBGCP4 TXLNA TXLNB UBE2H UBE2I UBE2U UBE3C UBTFL1 USO1 USP15 USP2 UTP14C UTP23 VPS28 VPS37C WASHC3 WHRN WT1 XIAP YJU2 YTHDC1 ZBTB16 ZBTB4 ZBTB42 ZC2HC1C ZFC3H1 ZFHX3 ZFP2 ZFYVE26 ZG16B ZGPAT ZMAT1 ZMAT2 ZNF124 ZNF250 ZNF280C ZNF3 ZNF35 ZNF410 ZNF414 ZNF417 ZNF438 ZNF48 ZNF488 ZNF512B ZNF524 ZNF572 ZNF581 ZNF587 ZNF594 ZNF648 ZNF688 ZNF774 ZNF835 ZZZ3
Entrez ID		5300	2801
HPRD ID		03031	03989
Ensembl ID		ENSG00000127445	ENSG00000167110
Uniprot IDs		Q13526	Q08379
PDB IDs		1F8A 1I6C 1I8G 1I8H 1NMV 1NMW 1PIN 1ZCN 2F21 2ITK 2KBU 2KCF 2LB3 2M8I 2M8J 2M9E 2M9F 2M9I 2M9J 2N1O 2Q5A 2RUC 2RUD 2RUQ 2RUR 2XP3 2XP4 2XP5 2XP6 2XP7 2XP8 2XP9 2XPA 2XPB 2ZQS 2ZQT 2ZQU 2ZQV 2ZR4 2ZR5 2ZR6 3I6C 3IK8 3IKD 3IKG 3JYJ 3KAB 3KAC 3KAD 3KAF 3KAG 3KAH 3KAI 3KCE 3NTP 3ODK 3OOB 3TC5 3TCZ 3TDB 3WH0 4GWT 4GWV 4QIB 4TNS 4TYO 4U84 4U85 4U86 5B3W 5B3X 5B3Y 5B3Z 5BMY 5GPH 5UY9 5VTI 5VTJ 5VTK 6DUN 6O33 6O34 6SVC 6SVE 6SVH	4REY 6IW8 6IWA 6K06
Enriched GO Terms of Interacting Partners?
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