PIK3CA and NRAS

  • Data Source:
  • HPRD (in vitro, in vivo)

PIK3CA

NRAS

Description phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha NRAS proto-oncogene, GTPase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 70 interacting genes: ADAP1 AKT1 AMBP APLP2 APPL1 ARAF ATP5IF1 ATR BEX1 BEX2 CCND2 CSF1R CYTH2 CYTH3 DDX5 DNAJB6 EGFR FANCC FASLG FBP2 FTL GABRB1 GALNT12 GLIS2 GNAQ GRIN2B HRAS IL13RA2 IL24 IL3 IRS2 IRS4 ITIH1 KRAS LCK MAP2K1 MRAS MYC NEDD4L NEDD9 NRAS PDGFRA PDGFRB PDK1 PIK3R1 PIK3R3 PRKCD PSMC3IP PTPN11 RASD2 RASGRP3 RELA RPS20 RPS6KB1 SFRP4 SGK1 SH3KBP1 SMAD2 SMAD3 SNX9 SQSTM1 STAT1 STK11 THRSP TICAM1 TMOD1 TNFSF13 UFD1 UMPS VARS2 48 interacting genes: ACVR1 AKT1 ALDOB AOPEP ARAF ARHGAP4 BCL2 CCDC180 CORO2A CYLC2 DNAJB1 EEF1A1 FANCC FBP2 FRAT2 HEMGN HRAS LEF1 LZTR1 MAPK3 MAPKAP1 MTOR PIK3CA PIK3CG PLCE1 PPP2CB RACGAP1 RAF1 RAP1GDS1 RASA1 RASGRP2 RASSF5 RGL2 RGL3 RIN1 RPS20 SFRP4 SHOC2 SMAD1 SMAD4 SMURF2 SRI STX17 TDRD7 TRMO UBE2L3 WDR76 XPA
Entrez ID 5290 4893
HPRD ID 01382 01273
Ensembl ID ENSG00000121879 ENSG00000213281
Uniprot IDs P42336 Q4LE51 P01111 Q5U091
PDB IDs 2ENQ 2RD0 3HHM 3HIZ 3ZIM 4JPS 4L1B 4L23 4L2Y 4OVU 4OVV 4TUU 4TV3 4WAF 4YKN 4ZOP 5DXH 5DXT 5FI4 5ITD 5SW8 5SWG 5SWO 5SWP 5SWR 5SWT 5SX8 5SX9 5SXA 5SXB 5SXC 5SXD 5SXE 5SXF 5SXI 5SXJ 5SXK 5UBR 5UK8 5UKJ 5UL1 5XGH 5XGI 5XGJ 6GVF 6GVG 6GVH 6GVI 6NCT 6OAC 6PYS 2N9C 3CON 5UHV 6E6H 6MPP 6ULI 6ULK 6ULN 6ULR 6UON 6WGH 6ZIO 6ZIR 6ZIZ
Enriched GO Terms of Interacting Partners?
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