PI3 and LORICRIN

		PI3	LORICRIN
Description		peptidase inhibitor 3	loricrin cornified envelope precursor protein
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Region Extracellular Space Cytosol Extracellular Matrix	Cornified Envelope Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Structural Constituent Of Skin Epidermis	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Copulation Negative Regulation Of Endopeptidase Activity Peptide Cross-linking Antimicrobial Humoral Response Antibacterial Humoral Response Innate Immune Response Cornification	Cytoskeleton Organization Peptide Cross-linking Keratinocyte Differentiation Cornification
Pathways		Antimicrobial peptides Formation of the cornified envelope	Formation of the cornified envelope
Drugs
Diseases			Vohwinkel syndrome, including: Vohwinkel syndrome (VS); Vohwinkel syndrome with ichthyosis
GWAS		Bipolar disorder ( 31043756) Blood protein levels ( 30072576 29875488 28240269) Malaria ( 31844061)
Interacting Genes		5 interacting genes: CELA1 CSTA EVPL KRT1 LORICRIN	7 interacting genes: CSTA EVPL IVL KRT1 PI3 SPRR3 VIM
Entrez ID		5266	4014
HPRD ID		15947	01070
Ensembl ID		ENSG00000124102	ENSG00000203782
Uniprot IDs		P19957	P23490
PDB IDs		1FLE 2REL 6ATU
Enriched GO Terms of Interacting Partners?
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