PFKM and UBTD1

Data Source:
BioGRID (two hybrid)

		PFKM	UBTD1
Description		phosphofructokinase, muscle	ubiquitin domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol 6-phosphofructokinase Complex Membrane Apical Plasma Membrane
	Molecular Function	6-phosphofructokinase Activity Protein Binding ATP Binding Protein C-terminus Binding AMP Binding Kinase Binding Identical Protein Binding Metal Ion Binding Monosaccharide Binding Fructose Binding Fructose-6-phosphate Binding	Protein Binding
	Biological Process	Fructose 6-phosphate Metabolic Process Glycolytic Process Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Muscle Cell Cellular Homeostasis Glycolytic Process Through Fructose-6-phosphate Canonical Glycolysis
Pathways		Glycolysis
Drugs
Diseases		Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Immature fraction of reticulocytes ( 32888494) Longevity (90 years and older) ( 25199915) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Pulse pressure ( 30578418) Red blood cell count ( 32888494)	Obesity-related traits ( 23251661) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		19 interacting genes: ATP6V0A4 CAV3 DLC1 DYNLL1 FHL2 HGS LSM7 MAPK3 NDUFB2 NOS1 PCNA PDGFRL PFKL SFRP2 SFRP4 SIAH1 SUMO2 TEAD4 UBTD1	22 interacting genes: BCOR CD1A FZD5 KIAA2026 MID1 MID2 MRFAP1 MRFAP1L1 PFKM RANBP2 RNF10 RNF5 TEAD1 TP53BP2 TRAF6 TRIM39 TRIM50 UBE2D1 UBE2D2 UBE2D3 UBE2D4 WWP2
Entrez ID		5213	80019
HPRD ID		01988	08568
Ensembl ID		ENSG00000152556	ENSG00000165886
Uniprot IDs		A0A024R0Y5 A0A2R8Y891 P08237	Q9HAC8
PDB IDs		4OMT
Enriched GO Terms of Interacting Partners?
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