PFKL and PCNT

Data Source:
BioGRID (affinity chromatography technology)

		PFKL	PCNT
Description		phosphofructokinase, liver type	pericentrin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol 6-phosphofructokinase Complex Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Centrosome Centriole Cytosol Microtubule Membrane Centriolar Satellite
	Molecular Function	6-phosphofructokinase Activity Protein Binding ATP Binding AMP Binding Kinase Binding Identical Protein Binding Metal Ion Binding Monosaccharide Binding Fructose Binding Fructose-6-phosphate Binding	Protein Binding Calmodulin Binding Molecular Adaptor Activity
	Biological Process	Fructose 6-phosphate Metabolic Process Glycolytic Process Response To Glucose Fructose 1,6-bisphosphate Metabolic Process Neutrophil Degranulation Negative Regulation Of Insulin Secretion Canonical Glycolysis	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Spindle Organization Signal Transduction Regulation Of G2/M Transition Of Mitotic Cell Cycle Cilium Assembly Positive Regulation Of Intracellular Protein Transport Ciliary Basal Body-plasma Membrane Docking
Pathways		Neutrophil degranulation Glycolysis	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy
Drugs
Diseases			Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II) Seckel syndrome
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Rheumatoid arthritis ( 21505073)	Heel bone mineral density ( 30598549) Pre-treatment viral load in HIV-1 infection ( 31219150) Treatment resistant depression ( 30468137)
Interacting Genes		14 interacting genes: APP ATN1 COPS6 GTPBP3 KRTAP10-7 KRTAP4-12 KRTAP5-9 MYD88 PFKM PRPF40A SUMO2 TESK1 TNFAIP3 YWHAQ	11 interacting genes: AKAP9 CALM1 CALM2 CCP110 CEP55 DISC1 PCM1 TP53BP1 TUBG1 TUBGCP2 TUBGCP3
Entrez ID		5211	5116
HPRD ID		01385	05804
Ensembl ID		ENSG00000141959	ENSG00000160299
Uniprot IDs		P17858 Q7L2M7	O95613
PDB IDs
Enriched GO Terms of Interacting Partners?
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