PEX7 and ACAT1

Data Source:
BioGRID (two hybrid)

		PEX7	ACAT1
Description		peroxisomal biogenesis factor 7	acetyl-CoA acetyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol	Mitochondrion Mitochondrial Matrix Extracellular Exosome
	Molecular Function	Peroxisome Matrix Targeting Signal-2 Binding Protein Binding Enzyme Binding Protein Homodimerization Activity	Acetyl-CoA C-acetyltransferase Activity C-acetyltransferase Activity Potassium Ion Binding
	Biological Process	Neuron Migration Endochondral Ossification Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Peroxisome Organization Ether Lipid Biosynthetic Process Protein Import Into Peroxisome Matrix	Acetyl-CoA Biosynthetic Process Isoleucine Catabolic Process Fatty Acid Beta-oxidation Branched-chain Amino Acid Catabolic Process Coenzyme A Metabolic Process Coenzyme A Biosynthetic Process Cholesterol Esterification Acetyl-CoA Catabolic Process Ketone Body Biosynthetic Process Ketone Body Catabolic Process Ketone Body Metabolic Process Propionyl-CoA Biosynthetic Process
Pathways		Peroxisomal protein import Peroxisomal protein import	Branched-chain amino acid catabolism Utilization of Ketone Bodies Synthesis of Ketone Bodies
Drugs			Sulfasalazine Cannabidiol Medical Cannabis Nabiximols
Diseases		Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3) Refsum disease; Heredopathia atactica polyneuritiformis
GWAS		Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494)	Nonunion in individuals with fractures ( 30680360) Refractive error ( 32231278)
Interacting Genes		8 interacting genes: ACAT1 KDM1A PEX13 PEX14 PEX5 PEX5L PHYH PRMT6	4 interacting genes: AGXT PDP1 PEX7 PTPRF
Entrez ID		5191	38
HPRD ID		03454	01946
Ensembl ID		ENSG00000112357	ENSG00000075239
Uniprot IDs		O00628 Q6FGN1	A0A140VJX1 A0A5F9ZHJ0 P24752
PDB IDs			2F2S 2IB7 2IB8 2IB9 2IBU 2IBW 2IBY
Enriched GO Terms of Interacting Partners?
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