MAP3K20 and CCDC69

Data Source:
BioGRID (two hybrid)

		MAP3K20	CCDC69
Description		mitogen-activated protein kinase kinase kinase 20	coiled-coil domain containing 69
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Cytoplasm Midbody Spindle Midzone
	Molecular Function	Magnesium Ion Binding RNA Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding	Microtubule Binding
	Biological Process	DNA Damage Checkpoint Activation Of MAPKK Activity Protein Phosphorylation Cytoskeleton Organization Cell Cycle Arrest Activation Of JUN Kinase Activity Cell Death Cell Differentiation Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process Stress-activated MAPK Cascade Limb Development Cellular Response To Gamma Radiation Positive Regulation Of Mitotic DNA Damage Checkpoint	Spindle Midzone Assembly
Pathways
Drugs		Dasatinib Fostamatinib
Diseases
GWAS			Bulimia nervosa ( 23568457) Chronic obstructive pulmonary disease ( 30804561) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Loneliness (linear analysis) ( 27629369) Lymphocyte counts ( 32888494) Monocyte count ( 32888494 27863252) Neutrophil count ( 32888494) Obesity-related traits ( 23251661) Red cell distribution width ( 32888494) White blood cell count ( 32888494 27863252)
Interacting Genes		32 interacting genes: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 SRPK2 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP1 ZFP2 ZNF33A ZNF35 ZNF567 ZNF593 ZNF660 ZNF71 ZNF746 ZNF775	5 interacting genes: ACO1 MAP3K1 MAP3K20 PSMA3 SMURF1
Entrez ID		51776	26112
HPRD ID		11791	13152
Ensembl ID		ENSG00000091436	ENSG00000198624
Uniprot IDs		D4Q8H0 Q9NYL2	A6NI79 Q7L2X4
PDB IDs		5HES 5X5O 6JUT 6JUU
Enriched GO Terms of Interacting Partners?
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